V A Patel1, B S Oberman1, T T Zacharia2, H Isildak1. 1. Department of Surgery, Division of Otolaryngology - Head and Neck Surgery,Pennsylvania State University, College of Medicine,Hershey,USA. 2. Department of Radiology, Division of Neuroradiology,Pennsylvania State University, College of Medicine,Hershey,USA.
Abstract
OBJECTIVES: To identify and evaluate cranial magnetic resonance imaging findings associated with Ménière's disease. METHODS: Seventy-eight patients with a documented diagnosis of Ménière's disease and 35 controls underwent 1.5 T or 3 T magnetic resonance imaging of the brain. Patients also underwent otological, vestibular and audiometric examinations. RESULTS: Lack of visualisation of the left and right vestibular aqueducts was identified as statistically significant amongst Ménière's disease patients (left, p = 0.0001, odds ratio = 0.02; right, p = 0.0004, odds ratio = 0.03). Both vestibular aqueducts were of abnormal size in the Ménière's disease group, albeit with left-sided significance (left, p = 0.008, odds ratio = 10.91; right, p = 0.49, odds ratio = 2.47). CONCLUSION: Lack of vestibular aqueduct visualisation on magnetic resonance imaging was statistically significant in Ménière's disease patients compared to the general population. The study findings suggest that magnetic resonance imaging can be useful to rule out retrocochlear pathology and provide radiological data to support the clinical diagnosis of Ménière's disease.
OBJECTIVES: To identify and evaluate cranial magnetic resonance imaging findings associated with Ménière's disease. METHODS: Seventy-eight patients with a documented diagnosis of Ménière's disease and 35 controls underwent 1.5 T or 3 T magnetic resonance imaging of the brain. Patients also underwent otological, vestibular and audiometric examinations. RESULTS: Lack of visualisation of the left and right vestibular aqueducts was identified as statistically significant amongst Ménière's disease patients (left, p = 0.0001, odds ratio = 0.02; right, p = 0.0004, odds ratio = 0.03). Both vestibular aqueducts were of abnormal size in the Ménière's disease group, albeit with left-sided significance (left, p = 0.008, odds ratio = 10.91; right, p = 0.49, odds ratio = 2.47). CONCLUSION: Lack of vestibular aqueduct visualisation on magnetic resonance imaging was statistically significant in Ménière's disease patients compared to the general population. The study findings suggest that magnetic resonance imaging can be useful to rule out retrocochlear pathology and provide radiological data to support the clinical diagnosis of Ménière's disease.
Authors: David Bächinger; Ngoc-Nhi Luu; Judith S Kempfle; Samuel Barber; Daniel Zürrer; Daniel J Lee; Hugh D Curtin; Steven D Rauch; Joseph B Nadol; Joe C Adams; Andreas H Eckhard Journal: Otol Neurotol Date: 2019-06 Impact factor: 2.311
Authors: Samuel Mawuli Adadey; Edmond Wonkam-Tingang; Elvis Twumasi Aboagye; Daniel Wonder Nayo-Gyan; Maame Boatemaa Ansong; Osbourne Quaye; Gordon A Awandare; Ambroise Wonkam Journal: Life (Basel) Date: 2020-10-28