Impact and Management of Paravalvular Regurgitation After Transcatheter Aortic Valve Replacement.

Paravalvular regurgitation (PVR) is a frequent complication of transcatheter aortic valve replacement that has been shown to be associated with increased mortality. The objective of this article was to review the most up-to-date information about the impact and management of PVR. A multimodality, multiparametric, integrative approach including angiography, Doppler echocardiography, and/or cardiac MR is essential to accurately assess the severity of PVR and the underlying etiology. Corrective procedures such as balloon postdilation, valve-in-valve, or leak closure may be considered, depending on the severity, location, and etiology of PVR.