Literature DB >> 28578845

How Do Preoperative Medications Influence Outcomes After Total Joint Arthroplasty?

Bradley J Zarling1, Jakub Sikora-Klak2, Chris Bergum3, David C Markel4.   

Abstract

BACKGROUND: Recent health care policy changes require hospitals and physicians to demonstrate improved quality. In 2012, a prospective database was formed with the Blue Cross and Blue Shield of Michigan to improve quality of care. The purpose of this study was to analyze patient preoperative medication as predictors of outcomes after total joint arthroplasty.
METHODS: Data were collected on patient's preoperative medications from 2012 to 2015 using a total joint arthroplasty database. Medications were categorized as antiplatelet, antimicrobial, anticoagulant, narcotic, steroid, insulin, or oral diabetes medication. Outcomes included hospital length of stay (LOS), discharge disposition/destination, and 90-day readmission. Univariate and multivariate regression analyses were performed.
RESULTS: A total of 3959 patients were studied. Eighty percent (3163 patients) were discharged home. The remainder (795) went to an extended-care facility (ECF). Patients discharged to an ECF were taking more medications (1.13 vs 0.80 in total knee arthroplasty; 1.18 vs 0.83 in total hip arthroplasty; P <.001). Patients who were readmitted took more medications (1.0 vs 0.85; P <.01). There were more discharges to an ECF in narcotic, steroid, and diabetes medication users. Patients taking anticoagulants, narcotics, insulin, and antiplatelets had greater readmission rates. There was a significant correlation between the number of medications and an increased LOS.
CONCLUSION: Patients taking more medications were more frequently discharged to an ECF and had increased LOS and readmission rates. Narcotics and diabetic medications had the greatest influence. Category and quantity of preoperative medications can be used as predictors of outcomes after arthroplasty surgery.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  MARCQI; Michigan Arthroplasty Registry Collaborative Quality Initiative; preoperative medications; total joint arthroplasty

Mesh:

Substances:

Year:  2017        PMID: 28578845     DOI: 10.1016/j.arth.2017.04.031

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  6 in total

Review 1.  Meta-analysis of retrospective studies suggests that the pre-operative opioid use is associated with an increased risk of adverse outcomes in total hip and or knee arthroplasty.

Authors:  Liyile Chen; Qiuru Wang; Donghai Li; Changjun Chen; Qianhao Li; Pengde Kang
Journal:  Int Orthop       Date:  2021-02-16       Impact factor: 3.075

2.  Impact of preoperative opioid use on patient-reported outcomes following primary total knee arthroplasty.

Authors:  Vivek Singh; Benjamin Fiedler; Chelsea Sue Sicat; Andrew S Bi; James D Slover; William J Long; Ran Schwarzkopf
Journal:  Eur J Orthop Surg Traumatol       Date:  2022-05-24

3.  Chronic preoperative corticosteroid use is not associated with surgical site infection following revision total knee arthroplasty.

Authors:  Safa C Fassihi; Alex Gu; Dana A Perim; Chapman Wei; Seth Stake; Savyasachi Thakkar; Anthony S Unger; Michael P Ast; Peter K Sculco
Journal:  J Orthop       Date:  2020-01-28

4.  Preoperative medications is one of the factor affecting patient-reported outcomes after total hip arthroplasty.

Authors:  Takanori Miura; Hiroaki Kijima; Natsuo Konishi; Hitoshi Kubota; Shin Yamada; Hiroshi Tazawa; Takayuki Tani; Norio Suzuki; Keiji Kamo; Masashi Fujii; Ken Sasaki; Tetsuya Kawano; Yosuke Iwamoto; Itsuki Nagahata; Naohisa Miyakoshi; Yoichi Shimada
Journal:  J Orthop       Date:  2020-12-30

5.  Effects of Preoperative Antiplatelet Agents and Anticoagulants on Total Joint Arthroplasty Outcomes.

Authors:  Gonzalo Sumarriva; Alexander Habashy; Tara Saxena; George Chimento
Journal:  Ochsner J       Date:  2021

6.  Fluctuation of visual analog scale pain scores and opioid consumption before and after total hip arthroplasty.

Authors:  Vivek Singh; Alex Tang; Thomas Bieganowski; Utkarsh Anil; William Macaulay; Ran Schwarzkopf; Roy I Davidovitch
Journal:  World J Orthop       Date:  2022-08-18
  6 in total

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