Literature DB >> 28578747

The Decomposition of Shared Environmental Influences on Externalizing Syndromes in the Swedish Population: A Multivariate Study.

Henrik Ohlsson1, Kenneth S Kendler2, Paul Lichtenstein3, Jan Sundquist1, Kristina Sundquist1.   

Abstract

Using information from Swedish population registries, we attempt to decompose the shared environment (C) into four subcomponents: close family, family, household, and community. Among pairs differing in their genetic and geographical/household relationships, we examine three externalizing syndromes: drug abuse (DA), criminal behavior (CB), and alcohol use disorders (AUD). The best-fitting common pathway model suggested that total estimates for C were higher for DA (21% for males and 18% for females) than for AUD (16% and 14%) and CB (17% and 10%). Concerning syndrome-specific influences in males, close family effects were stronger for CB and AUD, while community effects were stronger for DA. The two C components in between community experiences and close family experiences (family and household) were estimated to almost entirely derive from the common latent factor. In females, among the four components of C, the community experiences were just slightly above zero, while the C components referred to as the household effect were almost zero. The total close family experiences were similar and most important across syndromes were also divided into common and specific components. For all syndromes, for both males and females, the effects of additive genetic factors were 2-4 times the size of the total effect of the shared environment. Applying standard methods to novel relationships, we expand our understanding of how the shared environment contributes to individual differences in three externalizing syndromes.

Entities:  

Keywords:  close family; community; externalizing syndromes; family; household; shared environment

Mesh:

Year:  2017        PMID: 28578747      PMCID: PMC5551403          DOI: 10.1017/thg.2017.31

Source DB:  PubMed          Journal:  Twin Res Hum Genet        ISSN: 1832-4274            Impact factor:   1.587


  29 in total

1.  A Swedish national twin study of criminal behavior and its violent, white-collar and property subtypes.

Authors:  K S Kendler; H H Maes; S L Lönn; N A Morris; P Lichtenstein; J Sundquist; K Sundquist
Journal:  Psychol Med       Date:  2015-05-04       Impact factor: 7.723

2.  Rethinking environmental contributions to child and adolescent psychopathology: a meta-analysis of shared environmental influences.

Authors:  S Alexandra Burt
Journal:  Psychol Bull       Date:  2009-07       Impact factor: 17.737

3.  Neighborhood as a predictor of non-aggressive, but not aggressive, antisocial behaviors in adulthood.

Authors:  S A Burt; K L Klump; D A Kashy; D Gorman-Smith; J M Neiderhiser
Journal:  Psychol Med       Date:  2015-06-04       Impact factor: 7.723

4.  Environmental transmission of violent criminal behavior in siblings: a Swedish national study.

Authors:  K S Kendler; N A Morris; S L Lönn; J Sundquist; K Sundquist
Journal:  Psychol Med       Date:  2014-04-28       Impact factor: 7.723

5.  Genetic and family and community environmental effects on drug abuse in adolescence: a Swedish national twin and sibling study.

Authors:  Kenneth S Kendler; Hermine H Maes; Kristina Sundquist; Henrik Ohlsson; Jan Sundquist
Journal:  Am J Psychiatry       Date:  2014-02       Impact factor: 18.112

6.  Environmental clustering of drug abuse in households and communities: multi-level modeling of a national Swedish sample.

Authors:  Kenneth S Kendler; Henrik Ohlsson; Kristina Sundquist; Jan Sundquist
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2015-02-24       Impact factor: 4.328

7.  The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies.

Authors:  B Verhulst; M C Neale; K S Kendler
Journal:  Psychol Med       Date:  2014-08-29       Impact factor: 7.723

8.  A Swedish national adoption study of criminality.

Authors:  K S Kendler; S Larsson Lönn; N A Morris; J Sundquist; N Långström; K Sundquist
Journal:  Psychol Med       Date:  2013-11-04       Impact factor: 7.723

9.  A Swedish Population-Based Multivariate Twin Study of Externalizing Disorders.

Authors:  Kenneth S Kendler; Sara Larsson Lönn; Hermine H Maes; Paul Lichtenstein; Jan Sundquist; Kristina Sundquist
Journal:  Behav Genet       Date:  2015-10-22       Impact factor: 2.805

10.  Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

Authors:  S Hong Lee; Teresa R DeCandia; Stephan Ripke; Jian Yang; Patrick F Sullivan; Michael E Goddard; Matthew C Keller; Peter M Visscher; Naomi R Wray
Journal:  Nat Genet       Date:  2012-02-19       Impact factor: 38.330

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.