Literature DB >> 2857763

Early insight and the management of schizophrenic decompensation.

D W Heinrichs, B P Cohen, W T Carpenter.   

Abstract

Despite maintenance treatment, including the prophylactic use of neuroleptics, there is a significant rate of psychotic relapse and rehospitalization in schizophrenic outpatients. Thus comprehensive aftercare should ideally include clinical strategies of early intervention designed to abort decompensations in their earliest stages before florid psychosis and rehospitalization occur. Factors likely to improve the success rate of such strategies include the presence of a phase of prodromal symptoms preceding florid psychosis during which interventions could be made, as well as the patient's insight at such times that he/she is becoming ill, which would facilitate cooperation with intervention. While there is considerable evidence that a prodromal phase is typically present, there has been little exploration of "early insight." This study examines two hypotheses about early insight: 1) insight is present in a sizable portion of schizophrenic patients in the early phase of relapse; and 2) such early insight predicts a successful resolution of the relapse on an outpatient basis without the need for rehospitalization. In a retrospective research design utilizing clinical progress notes, both hypotheses were corroborated. Of the 38 patients in the sample, 24 (63%) demonstrated early insight, and of these only two (8%) were hospitalized as a result of the relapse. Conversely, seven of 14 (50%) uninsightful patients required rehospitalization (p = .006). This supports the feasibility of an early intervention strategy and confirms that early insight is an important patient attribute that predicts successful implementation of this treatment. Clinical experience in trying to develop early insight in the context of a psychotherapeutic relationship and the implications of early intervention for reducing the overall exposure to neuroleptics in schizophrenic populations are discussed.

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Year:  1985        PMID: 2857763     DOI: 10.1097/00005053-198503000-00001

Source DB:  PubMed          Journal:  J Nerv Ment Dis        ISSN: 0022-3018            Impact factor:   2.254


  18 in total

Review 1.  Poor insight in schizophrenia.

Authors:  X F Amador; D H Strauss
Journal:  Psychiatr Q       Date:  1993

2.  Impaired insight into illness and cognitive insight in schizophrenia spectrum disorders: resting state functional connectivity.

Authors:  Philip Gerretsen; Mahesh Menon; David C Mamo; Gagan Fervaha; Gary Remington; Bruce G Pollock; Ariel Graff-Guerrero
Journal:  Schizophr Res       Date:  2014-11-08       Impact factor: 4.939

3.  The relationship of insight to psychopathology in schizophrenia: a cross-sectional study.

Authors:  V M Aga; A K Agarwal; S C Gupta
Journal:  Indian J Psychiatry       Date:  1995-07       Impact factor: 1.759

4.  Insight and attitudes towards medication among inpatients with chronic schizophrenia in the US and China.

Authors:  Somaia Mohamed; Robert Rosenheck; Hongbo He; Ning Yuping
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2014-02-19       Impact factor: 4.328

5.  Perception of problems in psychiatric inpatients: denial, race and service usage.

Authors:  R E Perkins; P Moodley
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  1993-08       Impact factor: 4.328

6.  Cross-sectional and longitudinal relationships between insight and attitudes toward medication and clinical outcomes in chronic schizophrenia.

Authors:  Somaia Mohamed; Robert Rosenheck; Joseph McEvoy; Marvin Swartz; Scott Stroup; Jeffrey A Lieberman
Journal:  Schizophr Bull       Date:  2008-06-26       Impact factor: 9.306

7.  Modeling determinants of medication attitudes and poor adherence in early nonaffective psychosis: implications for intervention.

Authors:  Richard J Drake; Merete Nordentoft; Gillian Haddock; Celso Arango; W Wolfgang Fleischhacker; Birte Glenthøj; Marion Leboyer; Stefan Leucht; Markus Leweke; Phillip McGuire; Andreas Meyer-Lindenberg; Dan Rujescu; Iris E Sommer; René S Kahn; Shon W Lewis
Journal:  Schizophr Bull       Date:  2015-03-05       Impact factor: 9.306

8.  Prodromal signs of relapse in schizophrenia.

Authors:  N Tarrier; C Barrowclough; J S Bamrah
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  1991-08       Impact factor: 4.328

9.  Perceived vulnerability, relapse risk and coping in schizophrenia. An explorative study.

Authors:  I Thurm; H Haefner
Journal:  Eur Arch Psychiatry Neurol Sci       Date:  1987

10.  Prodromal symptoms in manic depressive psychosis.

Authors:  J A Smith; N Tarrier
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  1992-10       Impact factor: 4.328

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