Literature DB >> 28576909

Abciximab-induced delayed profound thrombocytopaenia.

Manar Jbara1, Sukhdeep Bhogal1, Kailash Bajaj2, Lovely Chhabra3.   

Abstract

Abciximab, the first approved glycoprotein (GP IIb/IIIa) inhibitor, is being widely used during acute coronary syndromes and offers the promising approach to antithrombotic therapy. We present a case of a young woman who initially received abciximab infusion for undergoing percutaneous coronary intervention of left anterior descending artery and was eventually diagnosed with abciximab-induced delayed thrombocytopaenia. This case outlines the importance of close follow-up of these patients to prevent serious adverse events. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  Cardiovascular system; Safety; Unwanted effects / adverse reactions

Mesh:

Substances:

Year:  2017        PMID: 28576909      PMCID: PMC5534833          DOI: 10.1136/bcr-2017-219379

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

Review 1.  Immune thrombocytopenia caused by glycoprotein IIb/IIIa inhibitors.

Authors:  Richard H Aster
Journal:  Chest       Date:  2005-02       Impact factor: 9.410

2.  Fatal delayed thrombocytopenia following abciximab therapy.

Authors:  Roger B McCorry; Paul Johnston
Journal:  J Invasive Cardiol       Date:  2006-06       Impact factor: 2.022

Review 3.  Drug-induced immune thrombocytopenia.

Authors:  Richard H Aster; Daniel W Bougie
Journal:  N Engl J Med       Date:  2007-08-09       Impact factor: 91.245

4.  Understanding the complexity of abciximab-related thrombocytopenia.

Authors:  Raffaele De Caterina; Marco Zimarino
Journal:  Thromb Haemost       Date:  2010-02-02       Impact factor: 5.249

5.  Acute profound thrombocytopenia secondary to local abciximab infusion.

Authors:  Matthew N Peters; Christopher D Press; John C Moscona; Rashad H Khazi Syed; Morgan J Katz; Alison A Egan; Mohannad B Bisharat; Vikram S Nijjar; Asif H Anwar
Journal:  Proc (Bayl Univ Med Cent)       Date:  2012-10

Review 6.  A practical approach to the diagnosis and management of thrombocytopenia associated with glycoprotein IIb/IIIa receptor inhibitors.

Authors:  J Llevadot; S A Coulter; R P Giugliano
Journal:  J Thromb Thrombolysis       Date:  2000-02       Impact factor: 2.300

7.  Drug-Induced Thrombocytopenia: Is it a Serious Concern for Glycoprotein IIb/IIIa Receptor Inhibitors?

Authors: 
Journal:  J Thromb Thrombolysis       Date:  1998-07       Impact factor: 2.300

8.  Delayed thrombocytopenia after treatment with abciximab: a distinct clinical entity associated with the immune response to the drug.

Authors:  B R Curtis; A Divgi; M Garritty; R H Aster
Journal:  J Thromb Haemost       Date:  2004-06       Impact factor: 5.824

9.  Abciximab-induced thrombocytopenia: management of bleeding in the setting of recent coronary stents.

Authors:  Kris Nowakowski; James Rogers; Gregory Nelson; Brendan Gunalingam
Journal:  J Interv Cardiol       Date:  2008-01-13       Impact factor: 2.279

Review 10.  Approach to the diagnosis and management of drug-induced immune thrombocytopenia.

Authors:  Donald M Arnold; Ishac Nazi; Theodore E Warkentin; James W Smith; Lisa J Toltl; James N George; John G Kelton
Journal:  Transfus Med Rev       Date:  2013-07-08
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