| Literature DB >> 28576740 |
Roland Thele1, Heidi Gumpert1, Louise B Christensen1, Peder Worning1, Kristian Schønning2, Henrik Westh3, Thomas A Hansen4.
Abstract
The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sensitive to Danish-registered antibiotics although it had a fosA-like gene in the genome. There were nine contigs that aligned to a plasmid, and these contigs contained several heavy metal resistance gene homologues. Furthermore, a prophage was discovered in the genome. WGS represents an efficient tool for monitoring Kluyvera spp. and its role as a reservoir of multidrug resistance. Therefore, this susceptible K. intermedia genome has many characteristics that allow comparison of resistant K. intermedia that might be discovered in the future.Entities:
Keywords: Abscess; Antibiotics; Cadmium; Kluyvera intermedia; Resistance; WGS
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Year: 2017 PMID: 28576740 DOI: 10.1016/j.jgar.2017.05.007
Source DB: PubMed Journal: J Glob Antimicrob Resist ISSN: 2213-7165 Impact factor: 4.035