Literature DB >> 28576740

Draft genome sequence of a Kluyvera intermedia isolate from a patient with a pancreatic abscess.

Roland Thele1, Heidi Gumpert1, Louise B Christensen1, Peder Worning1, Kristian Schønning2, Henrik Westh3, Thomas A Hansen4.   

Abstract

The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sensitive to Danish-registered antibiotics although it had a fosA-like gene in the genome. There were nine contigs that aligned to a plasmid, and these contigs contained several heavy metal resistance gene homologues. Furthermore, a prophage was discovered in the genome. WGS represents an efficient tool for monitoring Kluyvera spp. and its role as a reservoir of multidrug resistance. Therefore, this susceptible K. intermedia genome has many characteristics that allow comparison of resistant K. intermedia that might be discovered in the future.
Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Abscess; Antibiotics; Cadmium; Kluyvera intermedia; Resistance; WGS

Mesh:

Substances:

Year:  2017        PMID: 28576740     DOI: 10.1016/j.jgar.2017.05.007

Source DB:  PubMed          Journal:  J Glob Antimicrob Resist        ISSN: 2213-7165            Impact factor:   4.035


  7 in total

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Journal:  Front Microbiol       Date:  2022-09-06       Impact factor: 6.064

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Authors:  Sebastián Higuera-Llantén; Felipe Vásquez-Ponce; Beatriz Barrientos-Espinoza; Fernando O Mardones; Sergio H Marshall; Jorge Olivares-Pacheco
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  7 in total

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