Literature DB >> 2857606

Modulation of postjunctional alpha-adrenergic responsiveness by local changes in temperature.

P M Vanhoutte, J P Cooke, L E Lindblad, J T Shepherd, N A Flavahan.   

Abstract

In canine cutaneous veins, local moderate warming (37 degrees-41 degrees C) augments the responsiveness to postjunctional alpha 1-adrenergic stimulation but depresses that to postjunctional alpha 2-adrenergic activation. Moderate cooling (37 degrees-24 degrees C) has the opposite effect. The effects of warming and cooling on alpha 1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in alpha 2-adrenergic responsiveness.

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Year:  1985        PMID： 2857606     DOI： 10.1042/cs068s121

Source DB:  PubMed          Journal:  Clin Sci (Lond)        ISSN： 0143-5221            Impact factor:   6.124


  7 in total

1.  Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats.

Authors:  Tadachika Koganezawa; Tomohisa Ishikawa; Yukiyoshi Fujita; Tomonari Yamashita; Takako Tajima; Masaki Honda; Koichi Nakayama
Journal:  Br J Pharmacol       Date:  2006-05-15       Impact factor: 8.739

2.  The involvement of nitric oxide in the cutaneous vasoconstrictor response to local cooling in humans.

Authors:  Gary J Hodges; Kun Zhao; Wojciech A Kosiba; John M Johnson
Journal:  J Physiol       Date:  2006-05-25       Impact factor: 5.182

3.  Effect of skin temperature on cutaneous vasodilator response to the β-adrenergic agonist isoproterenol.

Authors:  Gary J Hodges; Dean L Kellogg; John M Johnson
Journal:  J Appl Physiol (1985)       Date:  2015-02-19

4.  Cutaneous neural activity and endothelial involvement in cold-induced vasodilatation.

Authors:  Gary J Hodges; Matthew M Mallette; Stephen S Cheung
Journal:  Eur J Appl Physiol       Date:  2018-03-02       Impact factor: 3.078

5.  Sustained cutaneous vasoconstriction during and following cyrotherapy treatment: Role of oxidative stress and Rho kinase.

Authors:  Kevin M Christmas; Jordan C Patik; Sepideh Khoshnevis; Kenneth R Diller; R Matthew Brothers
Journal:  Microvasc Res       Date:  2016-04-14       Impact factor: 3.514

6.  Nifedipine and alpha-adrenoceptor function in human finger skin vessels.

Authors:  L E Lindblad; L Ekenvall; B M Etzell
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

7.  Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice.

Authors:  M Honda; M Suzuki; K Nakayama; T Ishikawa
Journal:  Br J Pharmacol       Date:  2007-07-09       Impact factor: 8.739
  7 in total

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