F M Daray1, A L Rubinstein2, L Gutierrez2, F Lanas3, N Mores4, M Calandrelli5, R Poggio2, J Ponzo6, V E Irazola7. 1. University of Buenos Aires, School of Medicine, Institute of Pharmacology, Argentina; National Council of Scientific and Technical Research (CONICET), Argentina. 2. South American Center of Excellence in Cardiovascular Health (CESCAS), Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires, Argentina. 3. CIGES, Universidad de La Frontera (UFRO), Temuco, Chile. 4. Municipalidad de Marcos Paz, Pcia de Buenos Aires, Argentina. 5. Sanatorio San Carlos, Bariloche, Pcia de Río Negro, Argentina. 6. Facultad de Medicina, Universidad de la República, Uruguay. 7. South American Center of Excellence in Cardiovascular Health (CESCAS), Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires, Argentina. Electronic address: virazola@iecs.org.ar.
Abstract
BACKGROUND: Depression is one of the major contributors to the global burden of diseases; however, population-based data in South America are limited. METHODS: We conducted a population-based cross sectional study with 7524 participants, aged 35-74 years old, recruited between February 2010 and December 2011 from randomly selected samples in 4 cities (Bariloche and Marcos Paz, Argentina; Temuco, Chile; and Pando-Barros Blancos, Uruguay). Major Depressive Episode (MDE) was assessed using the Patient Health Questionnaire (PHQ) - 9. RESULTS: The overall prevalence of MDE was 14.6% (95% CI: 13.6, 15.6). However, there was a geographical variability of up to 3.7 folds between different cities being 5.6% (95% CI: 4.6, 6.7) in Marcos Paz, Argentina; 9.5% (95% CI: 8.2, 10.9) in Bariloche, Argentina; 18.1% (95% CI: 16.3, 20.0) in Temuco, Chile, and 18.2 (95% CI: 16.3, 20.2) in Pando-Barros Blancos, Uruguay. The multivariate model showed that, adjusted by location, being female, being between 35 and 44 years old, having experienced at least one stressful life event, currently smoking, and having a history of chronic medical diseases were independently associated with an increased risk of MDE, while having higher education and being married or living with a partner reduced the risk of MDE. LIMITATIONS: These results are representative of the selected cities included in the study. As such extrapolation to the general populations of Argentina, Chile, and Uruguay should be done with caution CONCLUSIONS: This study showed a high prevalence and variability of MDE in the Southern Cone of Latin America.
BACKGROUND:Depression is one of the major contributors to the global burden of diseases; however, population-based data in South America are limited. METHODS: We conducted a population-based cross sectional study with 7524 participants, aged 35-74 years old, recruited between February 2010 and December 2011 from randomly selected samples in 4 cities (Bariloche and Marcos Paz, Argentina; Temuco, Chile; and Pando-Barros Blancos, Uruguay). Major Depressive Episode (MDE) was assessed using the Patient Health Questionnaire (PHQ) - 9. RESULTS: The overall prevalence of MDE was 14.6% (95% CI: 13.6, 15.6). However, there was a geographical variability of up to 3.7 folds between different cities being 5.6% (95% CI: 4.6, 6.7) in Marcos Paz, Argentina; 9.5% (95% CI: 8.2, 10.9) in Bariloche, Argentina; 18.1% (95% CI: 16.3, 20.0) in Temuco, Chile, and 18.2 (95% CI: 16.3, 20.2) in Pando-Barros Blancos, Uruguay. The multivariate model showed that, adjusted by location, being female, being between 35 and 44 years old, having experienced at least one stressful life event, currently smoking, and having a history of chronic medical diseases were independently associated with an increased risk of MDE, while having higher education and being married or living with a partner reduced the risk of MDE. LIMITATIONS: These results are representative of the selected cities included in the study. As such extrapolation to the general populations of Argentina, Chile, and Uruguay should be done with caution CONCLUSIONS: This study showed a high prevalence and variability of MDE in the Southern Cone of Latin America.
Authors: Fernando Torrente; Adrian Yoris; Daniel Low; Pablo Lopez; Pedro Bekinschtein; Gustavo H Vázquez; Facundo Manes; Marcelo Cetkovich Journal: BJPsych Open Date: 2021-12-10
Authors: Marcelo Machado de Almeida; Luís Augusto Vasconcelos da Silva; Francisco Inácio Bastos; Mark Drew Crosland Guimarães; Carolina Coutinho; Ana Maria de Brito; Socorro Cavalcante; Inês Dourado Journal: PLoS One Date: 2022-09-01 Impact factor: 3.752