Literature DB >> 28573306

Two-photon imaging of formaldehyde in live cells and animals utilizing a lysosome-targetable and acidic pH-activatable fluorescent probe.

Xilei Xie1, Fuyan Tang, Xiaoyan Shangguan, Shiyi Che, Jinye Niu, Yongsheng Xiao, Xu Wang, Bo Tang.   

Abstract

Lyso-TPFP presents lysosomal targetability and an acidic pH-activatable response toward formaldehyde. Thus, it exclusively visualizes lysosomal formaldehyde and is immune against it in neutral cytosol and other organelles. In addition, two-photon fluorescence imaging endows Lyso-TPFP with the capability of in situ tracking formaldehyde in live cells and animals.

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Year:  2017        PMID： 28573306     DOI： 10.1039/c7cc03050a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  Activity-Based Sensing Methods for Monitoring the Reactive Carbon Species Carbon Monoxide and Formaldehyde in Living Systems.

Authors:  Jun Ohata; Kevin J Bruemmer; Christopher J Chang
Journal:  Acc Chem Res       Date:  2019-09-05       Impact factor: 22.384

2.  pH-Responsive Fluorescence Enhanced Nanogel for Targeted Delivery of AUR and CDDP Against Breast Cancer.

Authors:  Zhiwen Cao; Wen Li; Rui Liu; Chenxi Li; Yurong Song; Guangzhi Liu; Youwen Chen; Cheng Lu; Aiping Lu; Yuanyan Liu
Journal:  Int J Nanomedicine       Date:  2020-10-29

3.  Chemiluminescent Probes for Activity-Based Sensing of Formaldehyde Released from Folate Degradation in Living Mice.

Authors:  Kevin J Bruemmer; Ori Green; Timothy A Su; Doron Shabat; Christopher J Chang
Journal:  Angew Chem Int Ed Engl       Date:  2018-04-27       Impact factor: 15.336

Review 4.  Fluorescent probes for organelle-targeted bioactive species imaging.

Authors:  Peng Gao; Wei Pan; Na Li; Bo Tang
Journal:  Chem Sci       Date:  2019-05-24       Impact factor: 9.825

5.  Aggregation-Induced Emission-Based Fluorescence Probe for Fast and Sensitive Imaging of Formaldehyde in Living Cells.

Authors:  Wen Chen; Junyan Han; Xiangnan Wang; Xianjun Liu; Feng Liu; Fenglin Wang; Ru-Qin Yu; Jian-Hui Jiang
Journal:  ACS Omega       Date:  2018-10-31

6.  A two-photon lysosome-targeted probe for endogenous formaldehyde in living cells.

Authors:  Ting Cao; Hong Ma
Journal:  RSC Adv       Date:  2022-06-20       Impact factor: 4.036

7.  Imaging of Formaldehyde in Live Cells and Daphnia magna via Aza-Cope Reaction Utilizing Fluorescence Probe With Large Stokes Shifts.

Authors:  Mingwang Yang; Jiangli Fan; Jianjun Du; Saran Long; Jia Wang; Xiaojun Peng
Journal:  Front Chem       Date:  2018-10-15       Impact factor: 5.221
  7 in total

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