Literature DB >> 28571299

Patient Centered Outcomes in Periodontal Treatment-An Evidenced Based Approach.

Ekta Bharatbhai Shah1, Bhavesh Bhupendrabhai Modi1, Monali Amit Shah2, Deepak Harishbhai Dave3.   

Abstract

Transformation of research into clinical practice is the most challenging step in evidence based dental practice. Designing the most reliable research with applicable endpoint evaluation is very important as it can lead to successful research outcomes that can be accepted in clinical practice. In the periodontal research few accepted endpoints are used frequently as they are believed to be the gold standard in measuring the periodontal disease and the treatment outcomes. However, a wide range of endpoints used are surrogate endpoints and these endpoints have no direct correlation with the patient centered outcomes. Hence, a direct relationship of surrogate endpoints with true endpoints needs to be established. This review highlights the importance of true endpoints and challenges in implementing these in clinical research. Importance of patient's centered outcomes are also reviewed and duly discussed here. Need for conducting research which includes the true endpoints or the surrogate endpoints with clinical applicability and tangible outcomes, was also suggested in this review.

Entities:  

Keywords:  Periodontal research; Surrogate endpoints; Tangible outcomes; True endpoints

Year:  2017        PMID: 28571299      PMCID: PMC5449945          DOI: 10.7860/JCDR/2017/24260.9631

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  20 in total

1.  The value and use of 'quality of life' measures in the primary dental care setting.

Authors:  C McGrath; R Bedi
Journal:  Prim Dent Care       Date:  1999-04

2.  Evidence-based medicine. A new approach to teaching the practice of medicine.

Authors: 
Journal:  JAMA       Date:  1992-11-04       Impact factor: 56.272

3.  Short-term effect of Keyes' approach to periodontal therapy compared with modified Widman flap surgery.

Authors:  S P Whitehead; T L Watts
Journal:  J Clin Periodontol       Date:  1987-11       Impact factor: 8.728

4.  Surrogate endpoints in clinical trials: definition and operational criteria.

Authors:  R L Prentice
Journal:  Stat Med       Date:  1989-04       Impact factor: 2.373

5.  Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis.

Authors:  B L Riggs; S F Hodgson; W M O'Fallon; E Y Chao; H W Wahner; J M Muhs; S L Cedel; L J Melton
Journal:  N Engl J Med       Date:  1990-03-22       Impact factor: 91.245

Review 6.  A survey of endpoint characteristics in periodontal clinical trials published 1988-1992, and implications for future studies.

Authors:  P P Hujoel; T A DeRouen
Journal:  J Clin Periodontol       Date:  1995-05       Impact factor: 8.728

7.  Patient perceptions of periodontal therapy completed in a periodontal practice.

Authors:  Oystein Fardal; Anne C Johannessen; Gerard J Linden
Journal:  J Periodontol       Date:  2002-09       Impact factor: 6.993

8.  Comparison between patient expectation before and satisfaction after periodontal surgical treatment.

Authors:  Jae-Mok Lee; Keun Bae Song; Hee Yong Sohn; Seong Hwa Jeong; Ho Kwen Kwon
Journal:  J Periodontol       Date:  2002-09       Impact factor: 6.993

9.  Global burden of oral conditions in 1990-2010: a systematic analysis.

Authors:  W Marcenes; N J Kassebaum; E Bernabé; A Flaxman; M Naghavi; A Lopez; C J L Murray
Journal:  J Dent Res       Date:  2013-05-29       Impact factor: 6.116

Review 10.  Assessment of oral health related quality of life.

Authors:  P Finbarr Allen
Journal:  Health Qual Life Outcomes       Date:  2003-09-08       Impact factor: 3.186

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