Literature DB >> 28571294

A Rare Case of Digoxin Associated Gingival Overgrowth.

Sanjeela Rakshith Guru1, Aparnna Suresh2, Shyam Padmanabhan3, Adithya Reddy4.   

Abstract

This case report presents a case of drug induced gingival overgrowth in a 28-year-old female patient with history of Coronary Artery Disease (CAD) and was prescribed digoxin in combination with furosemide and acitrom for the same. On clinical examination, the patient presented with severe gingival overgrowth. The volume of enlargement seen did not correlate solely with the diagnosis of inflammatory Gingival Enlargement (GE), hence an added drug induced component to the Gingival Overgrowth (GO) was suspected. It was decided to treat the condition using initial therapy {meticulous Scaling and Root Planning (SRP)} followed by a period of observation and maintenance. On recall, since there was no marked improvement, surgical intervention was planned. Periodic treatment combining surgery and maintenance ultimately produced the desired results clinically. Thus, this article within limits highlights that because of time-relationship between the starting of the medication that is digoxin and manifestation of GO, a causal relationship is likely.

Entities:  

Keywords:  Coronary artery disease; Gingival hyperplasia; Periodontitis

Year:  2017        PMID: 28571294      PMCID: PMC5449940          DOI: 10.7860/JCDR/2017/25858.9729

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  11 in total

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Journal:  J Periodontol       Date:  2004-10       Impact factor: 6.993

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Journal:  Mayo Clin Proc       Date:  1998-12       Impact factor: 7.616

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Authors:  Katarzyna Winnicka; Krzysztof Bielawski; Anna Bielawska; Wojciech Miltyk
Journal:  Nat Prod Res       Date:  2010-02       Impact factor: 2.861

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Authors:  Rashi Chaturvedi
Journal:  J Can Dent Assoc       Date:  2009-05       Impact factor: 1.316

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Authors:  Piero Casavecchia; M Ilhan Uzel; Alpdogan Kantarci; Hatice Hasturk; Serge Dibart; Thomas C Hart; Philip C Trackman; Thomas E Van Dyke
Journal:  J Periodontol       Date:  2004-05       Impact factor: 6.993

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