| Literature DB >> 28567280 |
Trevor Duke1,2, Ilomo Hwaihwanje3, Magdalynn Kaupa4, Jonah Karubi4, Doreen Panauwe5, Martin Sa'avu6, Francis Pulsan2, Peter Prasad7, Freddy Maru8, Henry Tenambo9, Ambrose Kwaramb9, Eleanor Neal1, Hamish Graham1, Rasa Izadnegahdar10.
Abstract
BACKGROUND: Pneumonia is the largest cause of child deaths in Papua New Guinea (PNG), and hypoxaemia is the major complication causing death in childhood pneumonia, and hypoxaemia is a major factor in deaths from many other common conditions, including bronchiolitis, asthma, sepsis, malaria, trauma, perinatal problems, and obstetric emergencies. A reliable source of oxygen therapy can reduce mortality from pneumonia by up to 35%. However, in low and middle income countries throughout the world, improved oxygen systems have not been implemented at large scale in remote, difficult to access health care settings, and oxygen is often unavailable at smaller rural hospitals or district health centers which serve as the first point of referral for childhood illnesses. These hospitals are hampered by lack of reliable power, staff training and other basic services.Entities:
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Year: 2017 PMID: 28567280 PMCID: PMC5441450 DOI: 10.7189/jogh.07.010411
Source DB: PubMed Journal: J Glob Health ISSN: 2047-2978 Impact factor: 4.413
Baseline data in 36 health centers and district hospitals
| Year | Paediatric admissions | Paediatric deaths | CFR (%) | Pneumonia | Pneumonia deaths | Pneumonia CFR (%) | Births | NND | NMR (per 1000) | Children referred out |
|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | 8511 | 309 | 3.63 | 3510 | 146 | 4.16 | 10933 | 98 | 9.0 | 687 |
| 2013 | 7193 | 236 | 3.28 | 2849 | 125 | 4.39 | 10329 | 88 | 8.5 | 695 |
| 2012 | 5104 | 216 | 4.23 | 2447 | 86 | 3.51 | 10284 | 84 | 8.2 | 791 |
NND – neonatal deaths, CFR – case fatality rate
Outcomes, research questions, sources of data and specific metrics
| Outcome category | Research questions | Sources of data | Metrics | |
|---|---|---|---|---|
| 1 | Deaths from pneumonia; overall pediatric deaths in health facility | Is there a difference in pneumonia case fatality rates and overall pediatric CFR from pre to post implementation of improved oxygen therapy and solar power? | Admission record books | |
| 2 | Referral / transfer | Is there any difference in referral rates from pre to post intervention? | Admission record books | Paediatric transfers / all pediatric admissions (%). |
| 3 | Patient characteristics and response to oxygen therapy – effectiveness of oxygen therapy using the method we have designed to treat hypoxaemia | What are the conditions associated with hypoxaemia in remote rural health facilities? What is the response to oxygen therapy when oxygen is given using solar–powered oxygen concentrators? What is the duration of hypoxaemia in children managed in remote rural health facilities? | Standardised admission record data | Diagnoses associated with hypoxaemia (proportions) disaggregated for neonates and children >1 mo. Response to oxygen therapy (median change in SpO2 in the first 30 min; and proportion responded / not responded, ie, proportion with persisting SpO2<90%, or severe signs of respiratory distress 30 min after commencing oxygen). Days of oxygen therapy. Duration of hypoxaemia for neonates and children >1 month. |
| 4 | Maintenance of oxygen equipment | Are concentrators maintained well, are problems identified and is appropriate action taken? What proportion of concentrators undergo weekly maintenance and performance checking? What problems are identified? What proportion of concentrators are functioning well after 1, 2 and 3 years since installation? | Oxygen concentrator performance log–books. On–site checks on support and monitoring visits | What proportion of oxygen concentrators undergo weekly maintenance and performance checking? List of problems identified and action taken. Number / proportion of concentrators providing >85% oxygen and reliable flow rates as checked by oxygen analyzer at 1, 2 and 3 years. |
| 5 | Health workers knowledge and skill of oxygen therapy | What is the oxygen knowledge and skill of the health workers in remote health facilities? Does this improve with training and CQI | Oxygen competency tests – repeated measures | Repeating oxygen knowledge and skill tests at 12 monthly intervals. |
| 6 | Reliability, efficiency and adequacy of solar power | Solar power output (quantitative kW hours per day), adequacy of this power for running concentrators and other equipment needed by the health facility, and any problems identified. | Tristar 60 Amp controller | |
| 7 | Training outcomes | What training was done and what are the perceived training needs? | Project records | Record of training courses conducted: formal; in–house as part of CQI |
| 8 | Sustainable processes | Is it sustainable in PNG to have concentrators run off solar power as the source of oxygen in remote areas? | Mixture of the above data sources, and documentation of relevant events, meetings and occurrences | How would we measure sustainability? |
| 9 | Wider benefits | Does CQI in rural health facilities improve wider outcomes? Care seeking by parents? Health worker morale? | Above data and qualitative assessments |
CQI – continuous quality improvement, CFR – case fatality rate, SpO2 – arterial oxygen saturation