Literature DB >> 28565896

Effects of magnetically controlled growing rods surgery on pulmonary function in young subjects with spinal muscular atrophy type 2 and other neuromuscular scoliosis.

Luca Colombo1, Carlotta Martini1, Chiara Bersanini2, Francesca Izzo2, Jorge H Villafañe3, Pedro Berjano1, Claudio Lamartina1.   

Abstract

BACKGROUND: The aim of this study was to determine the effects of magnetically controlled growing rods surgery (MCGRS) of the scoliosis on pulmonary function in children with neuromuscular scoliosis.
METHODS: Seven patients, 85.7% female (mean±SD age: 6.7±1.2 years), with neuromuscular scoliosis (4 SMA II, 2 congenital myopathies and 1 VACTER syndrome), received MCGRS of the spine in the thoraco-lumbar area. The outcome measures were clinical features and pulmonary function (forced vital capacity [FVC] and forced expiratory volume in 1st second [FEV1], were collected. All measures were collected at pre-, post-intervention and follow-up (short-term [0-6 months], mid-term [7-12 months], and long-term [13-24 months]).
RESULTS: MCGRS reduced Cobb angle after intervention in 100% in subjects and this result was maintained at 24-month follow-up (all, P=0.001). There was no significant difference in FVC or FEV1 between preoperative and each postoperative period, (P>0.05). Analyses of the correlation coefficients indicated no significant associations between changes in pulmonary function and scoliosis.
CONCLUSIONS: The current study found that MCGRS addressed to the scoliosis maintained pulmonary function during long-term follow-up; However, pulmonary function was not associated with scoiosis in children with neuromuscular scoliosis.

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Year:  2017        PMID: 28565896     DOI: 10.23736/S0390-5616.17.04052-8

Source DB:  PubMed          Journal:  J Neurosurg Sci        ISSN: 0390-5616            Impact factor:   2.279


  3 in total

1.  Surgical treatment of spinal deformities in spinal muscular atrophy: a single-center experience from China.

Authors:  Zhen Wang; Erwei Feng; Yang Jiao; Jiachen Lin; Junduo Zhao; Weiyun Chen; Jianxiong Shen
Journal:  Eur Spine J       Date:  2022-08-16       Impact factor: 2.721

2.  Impact of growth friendly interventions on spine and pulmonary outcomes of patients with spinal muscular atrophy.

Authors:  Ishaan Swarup; Elle M MacAlpine; Oscar H Mayer; Robert K Lark; John T Smith; Michael G Vitale; John M Flynn; Jason B Anari; Patrick J Cahill
Journal:  Eur Spine J       Date:  2020-08-18       Impact factor: 3.134

3.  Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era.

Authors:  Hak Sun Kim; Ji Won Kwon; Kun-Bo Park
Journal:  Neurospine       Date:  2022-01-29
  3 in total

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