| Literature DB >> 28564669 |
Steven A Toms1, Nikolaos Tapinos2.
Abstract
Gliomas are a class of primary brain tumors arising from the supporting structures of the brain, the astrocytes and oligodendrocytes, which range from benign lesions to its most malignant form, the glioblastoma. Treatment for these lesions includes maximal surgical resection, radiotherapy, and chemotherapy. Recently, novel therapies such as immune modulatory therapies and electrical field treatment of the most malignant form, the glioblastoma, have shown promise in improving survival. We will review recent advances in clinical trials, explore the role of multimodal care in brain tumor therapy, as well as explore advances in molecular biology and nanotechnology which offer new hope for treatment of this class of disease. [Full article available at http://rimed.org/rimedicaljournal-2017-06.asp].Entities:
Keywords: drug delivery; glioblastoma; immunotherapy; nanotechnology; tumor treating fields
Mesh:
Year: 2017 PMID: 28564669
Source DB: PubMed Journal: R I Med J (2013) ISSN: 0363-7913