Literature DB >> 2856383

Signal transduction during amoebal chemotaxis of Dictyostelium discoideum.

P C Newell1, G N Europe-Finner, N V Small.   

Abstract

Amoebae of the cellular slime mould Dictyostelium are chemotactically responsive to pulses of cyclic AMP produced by aggregation centres. Pulses of this nucleotide bind to the cell surface cyclic AMP receptors and induce a chain of intracellular events leading to actin polymerization, formation of cyclic GMP and specific induction of gene activity. An intermediary messenger is Ca2+ liberated from internal stores by inositol trisphosphate (IP3).

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Year:  1987        PMID： 2856383

Source DB:  PubMed          Journal:  Microbiol Sci        ISSN： 0265-1351


  3 in total

1.  Conditions that alter intracellular cAMP levels affect expression of the cAMP phosphodiesterase gene in Dictyostelium.

Authors:  B B Riley; S L Barclay
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

Review 2.  Genetics of early Dictyostelium discoideum development.

Authors:  R H Kessin
Journal:  Microbiol Rev       Date:  1988-03

3.  A pharmacologically distinct cyclic AMP receptor is responsible for the regulation of gp80 expression in Dictyostelium discoideum.

Authors:  P C Ma; C H Siu
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272
  3 in total

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