Literature DB >> 28561523

Absence of the alpha-1-antitrypsin PI*Z allele in Tunisia substantiates the particular genetic structure of African populations.

S Makni1, M Zitouni1, K Ayed1, S Mhirii2, S Azabi2, F Cherif2, M Maalej2, J P Martin3, R Sesboüé3.   

Abstract

Alpha-1-antitrypsin (PI) phenotypes were studied in a sample of 450 Tunisians. The observed frequencies of PI alleles were identical to those in African populations, with a very low incidence of PI*S and virtual absence of PI*Z. Such figures are similar to estimates in Asians and clearly opposite to those in Europeans. Am. J. Hum. Biol. 9:223-224, 1997. © 1997 Wiley-Liss, Inc.
Copyright © 1997 Wiley-Liss, Inc.

Entities:  

Year:  1997        PMID： 28561523     DOI： 10.1002/(SICI)1520-6300(1997)9:2<223::AID-AJHB8>3.0.CO;2-0

Source DB:  PubMed          Journal:  Am J Hum Biol        ISSN： 1042-0533            Impact factor:   1.937


  1 in total

1.  Alpha1 antitrypsin deficiency due to an homozygous PI* Null Q0Cairo mutation: Early onset of pulmonary manifestations and variability of clinical expression.

Authors:  Zineb Jouhadi; Marie Francoise Odou; Farid Zerimech; Ahmed Aziz Bousfiha; Nabiha Mikou; Nicole Porchet; Michel Crepin; Jilali Najib; Malika Balduyck
Journal:  Respir Med Case Rep       Date:  2018-04-10
  1 in total

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