| Literature DB >> 28560496 |
Jarosław Lewkowski1, Marta Morawska2, Rafał Karpowicz2, Piotr Rychter3, Diana Rogacz4, Kamila Lewicka4, Piotr Dobrzyński4,5.
Abstract
Six new dimethyl N-arylamino(2-pyrrolyl)methylphosphonates 2a-f were synthesized by the modified aza-Pudovik reaction. Their ecotoxicological impact using battery of bioassay was assessed using Microtox and Ostracodtoxit tests as well as phytotoxicity towards two plants, dicotyledonous radish (Raphanus sativus) and monocotyledonous oat (Avena sativa) following the OECD 208 Guideline. Ecotoxicological properties of compounds 2a-f in aspect of acute and chronic toxicity were evaluated using Heterocypris incongruens and Aliivibrio fisheri tests. The obtained results showed that tested aminophosphonates 2a-f have moderate-to-high phyto- and ecotoxicological impact. They are toxic for both plants but more toxic against dicotyledonous. The investigated compounds showed important ecotoxicity against Heterocypris incongruens crustaceans and Aliivibrio fisheri bacteria. It was found that the substituents of the phenyl ring plays a key role in the degree of toxicity. Results showed that investigated compounds are ecologically toxic and that any of their application should be implemented with care.Entities:
Keywords: Aliivibrio fisheri; Avena sativa; Ecotoxicity; Heterocypris incongruens; Pyrrole-derived aminophosphonates; Raphanus sativus
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Year: 2017 PMID： 28560496 DOI： 10.1007/s10646-017-1821-4
Source DB: PubMed Journal: Ecotoxicology ISSN： 0963-9292 Impact factor: 2.823