Literature DB >> 28560364

Copper-catalyzed acyltrifluoromethylation of alkenes: rapid access to trifluoroethyl indanones and related compounds.

Zhicheng Liu1, Yihui Bai, Jian Zhang, Yongqi Yu, Ze Tan, Gangguo Zhu.   

Abstract

Copper-catalyzed acyltrifluoromethylation of alkenes has been developed for the first time, affording trifluoroethyl indanones and related cyclic ketones in promising yields with excellent diastereoselectivity. The fast incorporation of CF3 and indanone into a single molecule renders it an efficient and valuable tool for the synthesis of biologically active compounds.

Entities:  

Year:  2017        PMID: 28560364     DOI: 10.1039/c7cc02537h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay.

Authors:  Xian Zhao; Hai-Yong Tu; Lei Guo; Shengqing Zhu; Feng-Ling Qing; Lingling Chu
Journal:  Nat Commun       Date:  2018-08-28       Impact factor: 14.919

  1 in total

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