This study demonstrates the potential applicability of the UV mutant Yarrowia lipolytica MK1 for the valorisation of glycerol and erythritol production in a chemostat culture. The aim of this research is to investigate the optimal C:N ratio in the feeding medium in order to enhance erythritol production. The highest erythritol concentration, at 113.1 g/L with a volumetric erythritol production rate of 1.1 g/(L·h) and a yield of 0.57 g/g, was obtained in the feeding medium with a C:N ratio of 80:1. Moreover, no residual glycerol was observed in the culture broth during cultivation. The chemical composition of the biomass was analysed. The contents of lysine and threonine in the biomass protein amino acid profile were higher than those required by the FAO/WHO for fodder yeast.
This study demonstrates the potential applicability of the UV mutant Yarrowia lipolytica MK1 for the valorisation of n class="Chemical">glycerol and erythritol production in a chemostat culture. The aim of this research is to investigate the optimal C:N ratio in the feeding medium in order to enhance erythritol production. The highest erythritol concentration, at 113.1 g/L with a volumetric erythritol production rate of 1.1 g/(L·h) and a yield of 0.57 g/g, was obtained in the feeding medium with a C:N ratio of 80:1. Moreover, no residual glycerol was observed in the culture broth during cultivation. The chemical composition of the biomass was analysed. The contents of lysine and threonine in the biomass protein amino acid profile were higher than those required by the FAO/WHO for fodder yeast.
Authors: I C Munro; W O Berndt; J F Borzelleca; G Flamm; B S Lynch; E Kennepohl; E A Bär; J Modderman; W O Bernt Journal: Food Chem Toxicol Date: 1998-12 Impact factor: 6.023
Authors: Margarida F Temudo; Rolf Poldermans; Robbert Kleerebezem; Mark C M van Loosdrecht Journal: Biotechnol Bioeng Date: 2008-08-15 Impact factor: 4.530
Authors: Magdalena Rakicka; Zbigniew Lazar; Thierry Dulermo; Patrick Fickers; Jean Marc Nicaud Journal: Biotechnol Biofuels Date: 2015-07-25 Impact factor: 6.040
Authors: Aleksandra M Mirończuk; Anna Biegalska; Karolina Zugaj; Dorota A Rzechonek; Adam Dobrowolski Journal: Front Microbiol Date: 2018-05-30 Impact factor: 5.640
Authors: Aleksandra M Mirończuk; Katarzyna E Kosiorowska; Anna Biegalska; Magdalena Rakicka-Pustułka; Mateusz Szczepańczyk; Adam Dobrowolski Journal: Microb Cell Fact Date: 2019-10-15 Impact factor: 5.328