I-Mei Lin1, Hsueh-Chen Lu1, Chih-Sheng Chu2,3, Chee-Siong Lee2, Ye-Hsu Lu2, Tsung-Hsien Lin2,4. 1. Department of Psychology, College of Humanities and Social Sciences, Kaohsiung Medical University. 2. Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital. 3. Division of Cardiology, Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital. 4. Department of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Abstract
BACKGROUND: Noninvasive brachial-ankle pulse wave velocity (baPWV) is an index for arterial stiffness in coronary artery disease (CAD). Depression has been connected to increased adverse cardiac events and mortality among patients with CAD. The aim of this study was to investigate the relationship between arterial stiffness and depressive symptoms among patients with CAD. METHODS: Eighty-six patients with CAD were recruited. Demographic characteristics and Beck Depressive Inventory II scores were obtained from the study participants, and resting baPWV was measured by using a noninvasive device. Thereafter, the participants were divided into mild and severe arteriosclerosis groups according to baPWV values. RESULTS: After adjusting the age, use of β-blockers, and left ventricular ejection fraction, there were higher somatic symptoms of depression in the severe arteriosclerosis group than those in the mild arteriosclerosis group, in particular concentration difficulty, changes in appetite, and fatigue. A multiple regression analysis indicated that baPWV was related to somatic symptoms of depression after adjusting the covariates of CAD risk factors. However, this association was not found between baPWV and cognitive symptoms of depression, and the total score of depression. CONCLUSIONS: This study supports the proposition that somatic symptom of depression was related to arterial stiffness among patients with CAD.
BACKGROUND: Noninvasive brachial-ankle pulse wave velocity (baPWV) is an index for arterial stiffness in coronary artery disease (CAD). Depression has been connected to increased adverse cardiac events and mortality among patients with CAD. The aim of this study was to investigate the relationship between arterial stiffness and depressive symptoms among patients with CAD. METHODS: Eighty-six patients with CAD were recruited. Demographic characteristics and Beck Depressive Inventory II scores were obtained from the study participants, and resting baPWV was measured by using a noninvasive device. Thereafter, the participants were divided into mild and severe arteriosclerosis groups according to baPWV values. RESULTS: After adjusting the age, use of β-blockers, and left ventricular ejection fraction, there were higher somatic symptoms of depression in the severe arteriosclerosis group than those in the mild arteriosclerosis group, in particular concentration difficulty, changes in appetite, and fatigue. A multiple regression analysis indicated that baPWV was related to somatic symptoms of depression after adjusting the covariates of CAD risk factors. However, this association was not found between baPWV and cognitive symptoms of depression, and the total score of depression. CONCLUSIONS: This study supports the proposition that somatic symptom of depression was related to arterial stiffness among patients with CAD.
Authors: Kosmas I Paraskevas; Ioannis Kotsikoris; Sotirios A Koupidis; Athanasios D Giannoukas; Dimitri P Mikhailidis Journal: Angiology Date: 2010-08 Impact factor: 3.619
Authors: Peter de Jonge; Johan Ormel; Rob H S van den Brink; Joost P van Melle; Titia A Spijkerman; Astrid Kuijper; Dirk J van Veldhuisen; Maarten P van den Berg; Adriaan Honig; Harry J G M Crijns; Aart H Schene Journal: Am J Psychiatry Date: 2006-01 Impact factor: 18.112
Authors: Etem Celik; Serkan Cay; Baris Sensoy; Sani Murat; Fatih Oksuz; Tayyar Cankurt; Mehmet Ali Mendi Journal: Acta Cardiol Sin Date: 2016-01 Impact factor: 2.672