Paul Saultier1, Claire Oudin1,2, Gérard Michel1,2. 1. 1 Department of Pediatric Hematology and Oncology, Timone Enfants Hospital, APHM and Aix Marseille Univ , Marseille, France . 2. 2 Research Unit EA 3279 and Department of Public Health, Aix Marseille Univ and Timone Hospital , APHM, Marseille, France .