Literature DB >> 28555698

A smart drug: a pH-responsive photothermal ablation agent for Golgi apparatus activated cancer therapy.

Fengfeng Xue1, Ying Wen, Peng Wei, Yilin Gao, Zhiguo Zhou, Shuzhang Xiao, Tao Yi.   

Abstract

We report a pH-responsive photothermal ablation agent (pH-PTT) based on cyanine dyes for photothermal therapy (PTT). The nanoparticles formed by BSA and pH-PTT preferentially accumulated in the Golgi apparatus of cancer cells compared to normal cells, and thus can be specifically activated by the acidic Golgi apparatus in cancer cells for effective PTT both ex vivo and in vivo.

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Year:  2017        PMID： 28555698     DOI： 10.1039/c7cc03168h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

Review 1.  Hydrogels for Antitumor and Antibacterial Therapy.

Authors:  Xiuling Fang; Cheng Wang; Shuwen Zhou; Pengfei Cui; Huaanzi Hu; Xinye Ni; Pengju Jiang; Jianhao Wang
Journal:  Gels       Date:  2022-05-19

Review 2.  Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting.

Authors:  Xianglei Fu; Yanbin Shi; Tongtong Qi; Shengnan Qiu; Yi Huang; Xiaogang Zhao; Qifeng Sun; Guimei Lin
Journal:  Signal Transduct Target Ther       Date:  2020-11-06

Review 3.  Subcellular Performance of Nanoparticles in Cancer Therapy.

Authors:  Chen-Guang Liu; Ya-Hui Han; Ranjith Kumar Kankala; Shi-Bin Wang; Ai-Zheng Chen
Journal:  Int J Nanomedicine       Date:  2020-02-05

Review 4.  The role of the Golgi apparatus in disease (Review).

Authors:  Jianyang Liu; Yan Huang; Ting Li; Zheng Jiang; Liuwang Zeng; Zhiping Hu
Journal:  Int J Mol Med       Date:  2021-02-04       Impact factor: 4.101

Review 5.  Solutions to the Drawbacks of Photothermal and Photodynamic Cancer Therapy.

Authors:  Xiangyu Deng; Zengwu Shao; Yanli Zhao
Journal:  Adv Sci (Weinh)       Date:  2021-01-05       Impact factor: 16.806

6.  Effective Chemotherapy of Lung Cancer Using Bovine Serum Albumin-Coated Hydroxyapatite Nanoparticles.

Authors:  Gongzhuo Li; Dongxin Tang; Dingxue Wang; Chuan Xu; Di Liu
Journal:  Med Sci Monit       Date:  2020-05-04

7.  Unsymmetrical pentamethine cyanines for visualizing physiological acidities from the whole-animal to the cellular scale with pH-responsive deep-red fluorescence.

Authors:  Yicheng Wang; Zuhai Lei; Cong Wang; Chong Cao; Jiayi Hu; Ling Du; Limei Han; Cong Li
Journal:  RSC Adv       Date:  2021-05-20       Impact factor: 3.361

8.  Photostable near-infrared-absorbing diradical-platinum(ii) complex solubilized by albumin toward a cancer photothermal therapy agent.

Authors:  Ryota Sawamura; Masataka Sato; Atsuko Masuya-Suzuki; Nobuhiko Iki
Journal:  RSC Adv       Date:  2020-02-11       Impact factor: 3.361

9.  γ-Glutamyl transpeptidase-activatable near-infrared nanoassembly for tumor fluorescence imaging-guided photothermal therapy.

Authors:  Fangyuan Zhou; Shikui Yang; Chao Zhao; Wangwang Liu; Xufeng Yao; Hui Yu; Xiaolian Sun; Yi Liu
Journal:  Theranostics       Date:  2021-05-13       Impact factor: 11.556

10.  HOCl-Activated Aggregation of Gold Nanoparticles for Multimodality Therapy of Tumors.

Authors:  Dongya Liu; Lingyan Liu; Feiyang Liu; Mengfan Zhang; Peng Wei; Tao Yi
Journal:  Adv Sci (Weinh)       Date:  2021-07-08       Impact factor: 16.806
  10 in total

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