Literature DB >> 28555682

Crosslinked shells for nano-assembled capsules: a new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities.

Annah Farashishiko1, Sally E Plush, Karley B Maier, A Dean Sherry, Mark Woods.   

Abstract

Nano-assembled capsules can incorporate large payloads of high relaxivity Gd3+, permitting the development of highly detectable molecular imaging agents for MRI. A new encapsulating shell, based upon cross-linked peptides, is found to afford smaller capsules (127 nm average diameter) with exceptionally high per-Gd3+ relaxivities (70.7 s-1 mmolal-1).

Entities:  

Year:  2017        PMID： 28555682      PMCID： PMC5580261          DOI： 10.1039/c7cc00123a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  17 in total

1.  Supramolecular adducts between poly-L-arginine and [TmIIIdotp]: a route to sensitivity-enhanced magnetic resonance imaging-chemical exchange saturation transfer agents.

Authors:  Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Journal:  Angew Chem Int Ed Engl       Date:  2003-09-29       Impact factor: 15.336

2.  Synthesis and relaxometric studies of a dendrimer-based pH-responsive MRI contrast agent.

Authors:  M Meser Ali; Mark Woods; Peter Caravan; Ana C L Opina; Marga Spiller; James C Fettinger; A Dean Sherry
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

Review 3.  Basic MR relaxation mechanisms and contrast agent design.

Authors:  Luis M De León-Rodríguez; André F Martins; Marco C Pinho; Neil M Rofsky; A Dean Sherry
Journal:  J Magn Reson Imaging       Date:  2015-05-14       Impact factor: 4.813

4.  Structure - relaxivity relationships among targeted MR contrast agents.

Authors:  Peter Caravan; Zhaoda Zhang
Journal:  Eur J Inorg Chem       Date:  2012-04       Impact factor: 2.524

5.  Rotational dynamics account for pH-dependent relaxivities of PAMAM dendrimeric, Gd-based potential MRI contrast agents.

Authors:  Sabrina Laus; Angélique Sour; Robert Ruloff; Eva Tóth; André E Merbach
Journal:  Chemistry       Date:  2005-05-06       Impact factor: 5.236

Review 6.  The synthesis and application of polyamino polycarboxylic bifunctional chelating agents.

Authors:  Luciano Lattuada; Alessandro Barge; Giancarlo Cravotto; Giovanni Battista Giovenzana; Lorenzo Tei
Journal:  Chem Soc Rev       Date:  2011-03-08       Impact factor: 54.564

7.  Maximizing the relaxivity of HSA-bound gadolinium complexes by simultaneous optimization of rotation and water exchange.

Authors:  Stefano Avedano; Lorenzo Tei; Alberto Lombardi; Giovanni B Giovenzana; Silvio Aime; Dario Longo; Mauro Botta
Journal:  Chem Commun (Camb)       Date:  2007-10-26       Impact factor: 6.222

8.  Nanoassembled capsules as delivery vehicles for large payloads of high relaxivity Gd3+ agents.

Authors:  Sally E Plush; Mark Woods; You-Fu Zhou; Shyam B Kadali; Michael S Wong; A Dean Sherry
Journal:  J Am Chem Soc       Date:  2009-11-04       Impact factor: 15.419

9.  Nano assembly and encapsulation; a versatile platform for slowing the rotation of polyanionic Gd(3+) -based MRI contrast agents.

Authors:  Annah Farashishiko; Kelly N Chacón; Ninian J Blackburn; Mark Woods
Journal:  Contrast Media Mol Imaging       Date:  2015-12-28       Impact factor: 3.161

Review 10.  A molecular imaging primer: modalities, imaging agents, and applications.

Authors:  Michelle L James; Sanjiv S Gambhir
Journal:  Physiol Rev       Date:  2012-04       Impact factor: 37.312
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  2 in total

1.  ParaCEST Agents Encapsulated in Reverse Nano-Assembled Capsules (RACs): How Slow Molecular Tumbling Can Quench CEST Contrast.

Authors:  Annah Farashishiko; Jacqueline R Slack; Mauro Botta; Mark Woods
Journal:  Front Chem       Date:  2018-04-06       Impact factor: 5.221

2.  Hydration number: crucial role in nuclear magnetic relaxivity of Gd(III) chelate-based nanoparticles.

Authors:  Rustem Zairov; Gulshat Khakimullina; Sergey Podyachev; Irek Nizameev; Georgy Safiullin; Rustem Amirov; Alberto Vomiero; Asiya Mustafina
Journal:  Sci Rep       Date:  2017-10-25       Impact factor: 4.379
  2 in total

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