Literature DB >> 28555649

Basic research: PHD inhibitors miss their mark.

Katharine H Wrighton.   

Abstract

Year:  2017        PMID： 28555649     DOI： 10.1038/nrneph.2017.75

Source DB:  PubMed          Journal:  Nat Rev Nephrol        ISSN： 1759-5061            Impact factor:   28.314


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  1 in total

1.  Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.

Authors:  Serafim Kiriakidis; Simon S Hoer; Natalie Burrows; Gloria Biddlecome; Moddasar N Khan; Cyrille C Thinnes; Christopher J Schofield; Norma Rogers; Marina Botto; Ewa Paleolog; Patrick H Maxwell
Journal:  Kidney Int       Date:  2017-05-12       Impact factor: 10.612
  1 in total

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