Literature DB >> 28554823

Mercury contamination in facial skin lightening creams and its health risks to user.

Yu Bin Ho1, Nor Hidayu Abdullah2, Hazwanee Hamsan2, Eugenie Sin Sing Tan3.   

Abstract

This study aims to determine concentrations of mercury in facial skin lightening cream according to different price categories (category I: <RM29.99, category II: RM30.00-RM59.99, category III: RM60.00-RM99.99 and category IV: ≥RM100.00) and their potential health risks to users. Prices of skin lightening creams were determined during a preliminary market survey. Thereafter, twenty samples were purchased from various locations such as cosmetic stalls, beauty shops, pharmacies and street vendors based on their stratified price categories. Samples were extracted using microwave digester and analyzed using cold vapor atomic absorption spectrometry (CV-AAS). Non-carcinogenic chronic health risks for application of facial skin lightening cream were calculated using Dermal Absorption Dose (DAD) and Hazard Quotient (HQ). Concentrations of mercury in samples were less than the United States Food and Drug Administration (USFDA) permitted trace levels (<1 ppm) except for one sample from category III which was manufactured in China. Concentrations of mercury in facial skin lightening creams ranged from not detected to 1.13 mg kg-1. There was no significant association between concentrations of mercury with price categories (p = 0.12). There was no significant non-carcinogenic health risk due to daily application of the facial skin lightening creams based on assumption of 30 years exposure period (HQ < 1).
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cold vapor atomic absorption spectrometry (CV-AAS); Hazard quotient (HQ); Mercury

Mesh:

Substances:

Year:  2017        PMID: 28554823     DOI: 10.1016/j.yrtph.2017.05.018

Source DB:  PubMed          Journal:  Regul Toxicol Pharmacol        ISSN: 0273-2300            Impact factor:   3.271


  5 in total

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Authors:  Nunthiya Deepuppha; Arnont Thongsaw; Boonjira Rutnakornpituk; Wipharat Chuachuad Chaiyasith; Metha Rutnakornpituk
Journal:  Environ Sci Pollut Res Int       Date:  2020-01-25       Impact factor: 4.223

2.  Investigation of the potential human health risk of toxic mercury determined in the grapevine exposed to mine gallery waters.

Authors:  Murat Topal
Journal:  J Food Sci Technol       Date:  2020-08-05       Impact factor: 2.701

3.  Mercury Exposure Associated with Use of Skin Lightening Products in Jamaica.

Authors:  Phylicia Ricketts; Christopher Knight; Andre Gordon; Ana Boischio; Mitko Voutchkov
Journal:  J Health Pollut       Date:  2020-05-04

4.  Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring.

Authors:  Gasem Mohammad Abu-Taweel
Journal:  Saudi J Biol Sci       Date:  2018-10-31       Impact factor: 4.219

5.  Epidemiology, clinical presentation, treatment, and follow-up of chronic mercury poisoning in China: a retrospective analysis.

Authors:  Sun Yawei; Long Jianhai; Zhao Junxiu; Peng Xiaobo; Qiu Zewu
Journal:  BMC Pharmacol Toxicol       Date:  2021-05-03       Impact factor: 2.483

  5 in total

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