Literature DB >> 28550902

Quantification of the vasodilatory effect of axillary plexus block. A prospective controlled study.

Andrea Wenger1, Jens Rothenberger2, Lara-Elena Hakim-Meibodi3, Thomas Notheisen4, Hans-Eberhard Schaller2.   

Abstract

BACKGROUND: Axillary plexus block is a common method for regional anesthesia, especially in hand and wrist surgery. Local anesthetics (e.g., mepivacaine) are injected around the peripheral nerves in the axilla. A vasodilatory effect due to sympathicolysis has been described, but not quantified.
MATERIALS AND METHODS: In a prospective controlled study between October 2012 and July 2013, we analyzed 20 patients with saddle joint arthritis undergoing trapeziectomy under axillary plexus block. Patients received a mixture of mepivacaine 1% and ropivacaine 0.75% in a 3:1 ratio. The measurements were carried out on the plexus side and the contralateral hand, which acted as the control. Laser-Doppler spectrophotometry (oxygen to see [O2C] device) was used to measure various perfusion factors before and after the plexus block, after surgery and in 2-h intervals until 6 h postoperatively.
RESULTS: Compared with the contralateral side, the plexus block produced an enhancement of tissue oxygen saturation of 117.35 ± 34.99% (cf. control SO2: 92.92 ± 22.30%, P < 0.010) of the baseline value. Furthermore, blood filling of microvessels (rHb: 131.36 ± 48.64% versus 109.12 ± 33.25%, P < 0.0062), peripheral blood flow (219.85 ± 165.59% versus 129.55 ± 77.12%, P < 0.018), and velocity (163.86 ± 58.18% versus 117.16 ± 45.05%, P < 0.006) showed an increase of values.
CONCLUSIONS: Axillary plexus block produces an improvement of peripheral tissue oxygen saturation of the upper extremity over the first 4 h after the inception of anesthesia.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Axillary plexus block; Laser-Doppler; Microcirculation; Oxygen saturation; Vasodilation

Mesh:

Substances:

Year:  2017        PMID: 28550902     DOI: 10.1016/j.jss.2017.01.009

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  2 in total

1.  Peripheral Nerve Blockade with Combined Standard and Liposomal Bupivacaine in Major Lower-Extremity Amputation.

Authors:  Catalina I Dumitrascu; Nafisseh S Warner; Thomas M Stewart; Adam W Amundson; Danette L Bruns; Andrew C Hanson; Phillip J Schulte; Mark M Smith; Michael J Brown; Adam D Niesen; Carlos B Mantilla; Matthew A Warner
Journal:  Pain Pract       Date:  2020-11-04       Impact factor: 3.183

2.  Improvement of Superficial and Deep Cutaneous Microcirculation Due to Axillary Plexus Anesthesia Impaired by Smoking.

Authors:  Talia Bosselmann; Jonas Kolbenschlag; Ole Goertz; Peter Zahn; Lukas Prantl; Marcus Lehnhardt; Björn Behr; Alexander Sogorski
Journal:  J Clin Med       Date:  2021-05-14       Impact factor: 4.241

  2 in total

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