Na Zhao1, Xiaohong Wang1, Wenyuan Wu2, Yongdong Hu3, Yajuan Niu4, Xueyi Wang5, Chengge Gao6, Ning Zhang7, Yiru Fang8, Jizhong Huang8, Tiebang Liu9, Fujun Jia10, Xuequan Zhu11, Jian Hu12, Gang Wang13. 1. Department of Psychiatry, the First Affiliated Hospital of Harbin Medical University, Harbin, China. 2. Department of Psychiatry, Tongji Hospital of Tongji University, Shanghai, China. 3. Department of Clinical Psychology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. 4. Department of Psychiatry, Beijing HuiLongGuan Hospital, Beijing, China. 5. Department of Psychiatry, the First Hospital of Hebei Medical University, Hebei, China. 6. Department of Psychiatry, the First Affiliated Hospital of Xi'an JiaoTong University, Xi'an, China. 7. Department of Psychiatry, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China. 8. Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 9. Department of Psychiatry, Shenzhen Kangning Hospital, Shenzhen, China. 10. Department of Psychiatry, Guangdong Mental Health Center, Guangdong General Hospital, Guangzhou, China. 11. National Clinical Research Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China. 12. Department of Psychiatry, the First Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address: drhujian@outlook.com. 13. National Clinical Research Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China; Center of Depression, Beijing Institute for Brain Disorders, Beijing, China. Electronic address: gangwangdoc@gmail.com.
Abstract
BACKGROUND: Depression is associated with substantial personal suffering and reduced quality of life and functioning. The aim of this study was to investigate gender differences on quality of life and functional impairment of outpatients with depression after acute phase treatment. METHODS: 1503 depression outpatients were recruited from eleven hospitals in China. Subjects were evaluated with sociodemographic characteristics, history and self-report instruments, related to severity of symptoms, function and quality of life. All data were analyzed to determine the gender differences. RESULTS: Men had a younger age at onset and the first onset age, higher education compared to women in total patients and with or without residual symptoms group. Using regression analysis, it was found that gender was significantly statistically related to severity scores of SDS and had no correlation with Q-LES-Q-SF total scores. In the residual symptoms group, greater functional impairment was noted by men in the area of work and social life. Significant gender differences of mood, work and sexual life in quality of life were observed. LIMITATIONS: This is a cross-sectional study of depressed outpatients and duration of acute phase treatment may not an adequate time to measure changes. CONCLUSIONS: Depression appears to affect men more seriously than women after acute phase treatment. Men had a younger age at onset and the first onset age, higher education, more functional impairment and lower satisfaction of quality of life in mood, work and sexual life. Gender differences affect acute treatment, remission and recovery.
BACKGROUND:Depression is associated with substantial personal suffering and reduced quality of life and functioning. The aim of this study was to investigate gender differences on quality of life and functional impairment of outpatients with depression after acute phase treatment. METHODS: 1503 depression outpatients were recruited from eleven hospitals in China. Subjects were evaluated with sociodemographic characteristics, history and self-report instruments, related to severity of symptoms, function and quality of life. All data were analyzed to determine the gender differences. RESULTS:Men had a younger age at onset and the first onset age, higher education compared to women in total patients and with or without residual symptoms group. Using regression analysis, it was found that gender was significantly statistically related to severity scores of SDS and had no correlation with Q-LES-Q-SF total scores. In the residual symptoms group, greater functional impairment was noted by men in the area of work and social life. Significant gender differences of mood, work and sexual life in quality of life were observed. LIMITATIONS: This is a cross-sectional study of depressed outpatients and duration of acute phase treatment may not an adequate time to measure changes. CONCLUSIONS:Depression appears to affect men more seriously than women after acute phase treatment. Men had a younger age at onset and the first onset age, higher education, more functional impairment and lower satisfaction of quality of life in mood, work and sexual life. Gender differences affect acute treatment, remission and recovery.
Authors: Alaor Ernst Schein; Amanda Gemelli; Bruna de Fátima Oliveira Wey; Sarah Galatto Cancillier; Kristian Madeira Journal: Rev Bras Med Trab Date: 2022-06-30