| Literature DB >> 28548244 |
Magda Zanelli1, Moira Ragazzi1, Giovanni Marchetti2, Alessandra Bisagni1, Massimo Principi3, Daniela Fanni4, Elisabetta Froio1, Silvia Serra1, Eleonora Zanetti1, Loredana De Marco1, Felice Giangaspero5,6, Stefano Ascani2.
Abstract
Histiocytic sarcoma is a rare malignant neoplasm arising most commonly in lymph nodes, intestinal tract, skin and soft tissue. The incidence of primary CNS histiocytic sarcoma is even rarer with a total of just 27 cases reported in the literature so far. Herein we describe the first autopsy case of histiocytic sarcoma presenting as a diffuse leptomeningeal disease in absence of a CNS tumor-forming parenchymal lesion. The clinical, pathological and immunophenotypic features are described and an updated literature review on primary CNS histiocytic sarcoma is included.Entities:
Keywords: brain; central nervous system; histiocytic sarcoma; malignant histiocytosis; meninges
Mesh:
Year: 2017 PMID: 28548244 DOI: 10.1111/neup.12390
Source DB: PubMed Journal: Neuropathology ISSN: 0919-6544 Impact factor: 1.906