Gerhard Schmalz1, Nora Schiffers1,2, Sandra Schwabe2, Radovan Vasko3, Gerhard A Müller3, Rainer Haak1, Rainer F Mausberg2, Dirk Ziebolz1. 1. Department of Cariology, Endodontology, and Periodontology, University of Leipzig, Leipzig, Germany. 2. Department of Preventive Dentistry, Periodontology, and Cariology, University Medical Center Goettingen, Goettingen, Germany. 3. Department of Nephrology and Rheumatology, University Medical Center Goettingen, Goettingen, Germany.
Abstract
OBJECTIVE: The aim of this cross-sectional study was to evaluate the dental and periodontal health, as well as the microbiological and salivary conditions, of patients with and without diabetes mellitus (DM) who are receiving haemodialysis. METHODS: One-hundred and fifty-nine haemodialysis patients were included and divided into groups according to the pre-existing diabetes status: DM or no DM. The oral examination included dental findings and assessment of the periodontal situation. The periodontal condition was classified as healthy/mild, moderate or severe periodontitis. Subgingival biofilm samples were analysed using the polymerase chain reaction. The salivary diagnostics included measurement of unstimulated and stimulated salivary flow, pH and buffer capacity. Statistical analyses used Fisher's test, the t-test and the Mann-Whitney U-test (α = 5%). RESULTS: The dental findings showed no significant difference between patients with and without DM (P = 0.44). The prevalence of periodontitis was high (96% in patients with DM and 97% in patients who did not have DM) and there was no significant difference between the groups (P = 0.71). There was a higher prevalence of Porphyromonas gingivalis, Parvimonas micros, Eubacterium nucleatum and Capnocytophaga spp. in patients without DM (P < 0.05). The salivary pH was significantly higher in patients without DM (P < 0.01). CONCLUSION: While differences in the prevalence of periodontal pathogenic bacteria and in the salivary pH were detected between the groups, the dental and periodontal status was comparable between patients with and without DM. Accordingly, DM appears to have no decisive influence on the oral health in patients treated with haemodialysis who have well-controlled diabetes.
OBJECTIVE: The aim of this cross-sectional study was to evaluate the dental and periodontal health, as well as the microbiological and salivary conditions, of patients with and without diabetes mellitus (DM) who are receiving haemodialysis. METHODS: One-hundred and fifty-nine haemodialysis patients were included and divided into groups according to the pre-existing diabetes status: DM or no DM. The oral examination included dental findings and assessment of the periodontal situation. The periodontal condition was classified as healthy/mild, moderate or severe periodontitis. Subgingival biofilm samples were analysed using the polymerase chain reaction. The salivary diagnostics included measurement of unstimulated and stimulated salivary flow, pH and buffer capacity. Statistical analyses used Fisher's test, the t-test and the Mann-Whitney U-test (α = 5%). RESULTS: The dental findings showed no significant difference between patients with and without DM (P = 0.44). The prevalence of periodontitis was high (96% in patients with DM and 97% in patients who did not have DM) and there was no significant difference between the groups (P = 0.71). There was a higher prevalence of Porphyromonas gingivalis, Parvimonas micros, Eubacterium nucleatum and Capnocytophaga spp. in patients without DM (P < 0.05). The salivary pH was significantly higher in patients without DM (P < 0.01). CONCLUSION: While differences in the prevalence of periodontal pathogenic bacteria and in the salivary pH were detected between the groups, the dental and periodontal status was comparable between patients with and without DM. Accordingly, DM appears to have no decisive influence on the oral health in patients treated with haemodialysis who have well-controlled diabetes.
Authors: C P Bots; J H G Poorterman; H S Brand; H Kalsbeek; B M van Amerongen; E C I Veerman; A V Nieuw Amerongen Journal: Oral Dis Date: 2006-03 Impact factor: 3.511
Authors: Suetonia C Palmer; Marinella Ruospo; Germaine Wong; Jonathan C Craig; Massimo Petruzzi; Michele De Benedittis; Pauline Ford; David W Johnson; Marcello Tonelli; Patrizia Natale; Valeria Saglimbene; Fabio Pellegrini; Eduardo Celia; Ruben Gelfman; Miguel R Leal; Marietta Torok; Paul Stroumza; Anna Bednarek-Skublewska; Jan Dulawa; Luc Frantzen; Juan Nin Ferrari; Domingo Del Castillo; Amparo G Bernat; Jorgen Hegbrant; Charlotta Wollheim; Letizia Gargano; Casper P Bots; Giovanni F M Strippoli Journal: Am J Kidney Dis Date: 2015-06-25 Impact factor: 8.860
Authors: Marinella Ruospo; Suetonia C Palmer; Jonathan C Craig; Giorgio Gentile; David W Johnson; Pauline J Ford; Marcello Tonelli; Massimo Petruzzi; Michele De Benedittis; Giovanni F M Strippoli Journal: Nephrol Dial Transplant Date: 2013-09-29 Impact factor: 5.992
Authors: G Schmalz; M Dietl; R Vasko; G-A Müller; L Rothermund; F Keller; D Ziebolz; F-M Rasche Journal: Med Oral Patol Oral Cir Bucal Date: 2018-11-01
Authors: Ilana Eshriqui; Heli T Viljakainen; Sandra R G Ferreira; Sajan C Raju; Elisabete Weiderpass; Rejane A O Figueiredo Journal: Int Breastfeed J Date: 2020-05-15 Impact factor: 3.461