Literature DB >> 28546727

Huge Carcinosarcoma of the Endolarynx: a Rare Tumour with Unusual Presentation.

Rakesh Kumar Singh1, Richi Sinha1, Anju Singh2, Sanjay Suman3, Madhu Priya1.   

Abstract

Carcinosarcoma or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma, which comprises 2 to 3 % of all laryngeal cancer. It is considered to be a biphasic tumour, composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. We present a case of huge carcinosarcoma of larynx in a 34 year-old male who developed severe stridor and dysphagia. The diagnosis was confirmed histopathologically, hence the disease was treated through total laryngectomy followed by adjuvant chemotherapy and radiotherapy. The patient is well and hearty for the past one and a half years.

Entities:  

Keywords:  Biphasic; Carcinosarcoma; Immunohistochemistry; Translarynx

Year:  2015        PMID: 28546727      PMCID: PMC5427011          DOI: 10.1007/s13193-015-0447-3

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  8 in total

1.  Spindle cell (sarcomatoid) carcinomas of the larynx: a clinicopathologic study of 187 cases.

Authors:  Lester D R Thompson; Jacqueline A Wieneke; Markku Miettinen; Dennis K Heffner
Journal:  Am J Surg Pathol       Date:  2002-02       Impact factor: 6.394

2.  Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.

Authors:  J E Lewis; K D Olsen; T J Sebo
Journal:  Hum Pathol       Date:  1997-06       Impact factor: 3.466

3.  Spindle cell carcinoma of the larynx and hypopharynx.

Authors:  K D Olsen; J E Lewis; V J Suman
Journal:  Otolaryngol Head Neck Surg       Date:  1997-01       Impact factor: 5.591

4.  Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: a clinicopathologic study of 20 cases.

Authors:  G S Leventon; H L Evans
Journal:  Cancer       Date:  1981-08-15       Impact factor: 6.860

5.  Spindle-cell carcinoma of the upper aerodigestive tract mucosa. An immunohistologic and ultrastructural study of 18 biphasic tumors and comparison with seven monophasic spindle-cell tumors.

Authors:  R J Zarbo; J D Crissman; H Venkat; M A Weiss
Journal:  Am J Surg Pathol       Date:  1986-11       Impact factor: 6.394

6.  Spindle-cell carcinoma of the aerodigestive tract. An immunohistochemical analysis of 21 cases.

Authors:  G L Ellis; J M Langloss; D K Heffner; V J Hyams
Journal:  Am J Surg Pathol       Date:  1987-05       Impact factor: 6.394

7.  Differential diagnosis of laryngeal spindle cell carcinoma and inflammatory myofibroblastic tumor--report of two cases with similar morphology.

Authors:  Hans-Ullrich Völker; Matthias Scheich; Sylvia Höller; Philipp Ströbel; Rudolf Hagen; Hans Konrad Müller-Hermelink; Matthias Eck
Journal:  Diagn Pathol       Date:  2007-01-09       Impact factor: 2.644

8.  A spindle cell carcinoma presenting with osseous metaplasia in the gingiva: a case report with immunohistochemical analysis.

Authors:  Naoki Katase; Ryo Tamamura; Mehmet Gunduz; Jun Murakami; Jun-Ichi Asaumi; Goichi Tsukamoto; Akira Sasaki; Hitoshi Nagatsuka
Journal:  Head Face Med       Date:  2008-12-01       Impact factor: 2.151

  8 in total

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