Lone Hellström 1 , Per Bech 2 , Carsten Hjorthøj 1 , Merete Nordentoft 1 , Jane Lindschou 3 , Lene Falgaard Eplov 1 Show Affiliations »
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OBJECTIVES: The effect of Individual Placement and Support (IPS ) on return to work or education among people with mood or anxiety disorders is unclear, while IPS increases return to work for people with severe mental illness . We examined the effect of IPS modified for people with mood and anxiety disorders (IPS-MA ) on return to work and education compared with services as usual (SAU). METHODS: In a randomised clinical superiority trial, 326 participants with mood and anxiety disorders were centrally randomised to IPS-MA, consisting of individual mentor support and career counselling (n=162) or SAU (n=164). The primary outcome was competitive employment or education at 24 months, while weeks of competitive employment or education, illness symptoms and level of functioning, and well-being were secondary outcomes . RESULTS: After 24 months, 44.4% (72/162) of the participants receiving IPS-MA had returned to work or education compared with 37.8% (62/164) following SAU (OR=1.34, 95% CI: 0.86 to 2.10, p=0.20). We found no difference in mean number of weeks in employment or education (IPS-MA 32.4 weeks vs SAU 26.7 weeks, p=0.14), level of depression (Hamilton Depression 6-Item Scale score IPS-MA 5.7 points vs SAU 5.0 points, p=0.12), level of anxiety (Hamilton Anxiety 6-Item Scale score IPS -MA 5.8 points vs SAU 5.1 points, p=0.17), level of functioning (Global Assessment of Functioning IPS -MA 59.1 points vs SAU 59.5 points, p=0.81) or well-being measured by WHO-Five Well-being Index (IPS-MA 49.6 points vs SAU 48.5 points, p=0.83) at 24 months. CONCLUSION: The modified version of IPS, IPS-MA, was not superior to SAU in supporting people with mood or anxiety disorders in return to work at 24 months. TRIAL REGISTRATION NUMBER: NCT01721824. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
RCT Entities: Population
Interventions
Outcomes
OBJECTIVES: The effect of Individual Placement and Support (IPS ) on return to work or education among people with mood or anxiety disorders is unclear, while IPS increases return to work for people with severe mental illness . We examined the effect of IPS modified for people with mood and anxiety disorders (IPS-MA ) on return to work and education compared with services as usual (SAU ). METHODS: In a randomised clinical superiority trial, 326 participants with mood and anxiety disorders were centrally randomised to IPS-MA , consisting of individual mentor support and career counselling (n=162) or SAU (n=164). The primary outcome was competitive employment or education at 24 months, while weeks of competitive employment or education, illness symptoms and level of functioning, and well-being were secondary outcomes. RESULTS: After 24 months, 44.4% (72/162) of the participants receiving IPS-MA had returned to work or education compared with 37.8% (62/164) following SAU (OR=1.34, 95% CI: 0.86 to 2.10, p=0.20). We found no difference in mean number of weeks in employment or education (IPS-MA 32.4 weeks vs SAU 26.7 weeks, p=0.14), level of depression (Hamilton Depression 6-Item Scale score IPS-MA 5.7 points vs SAU 5.0 points, p=0.12), level of anxiety (Hamilton Anxiety 6-Item Scale score IPS-MA 5.8 points vs SAU 5.1 points, p=0.17), level of functioning (Global Assessment of Functioning IPS-MA 59.1 points vs SAU 59.5 points, p=0.81) or well-being measured by WHO-Five Well-being Index (IPS-MA 49 .6 points vs SAU 48.5 points, p=0.83) at 24 months. CONCLUSION: The modified version of IPS , IPS-MA , was not superior to SAU in supporting people with mood or anxiety disorders in return to work at 24 months. TRIAL REGISTRATION NUMBER: NCT01721824. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Entities: Chemical
Disease
Species
Keywords:
Supported employment; affective disorder; anxiety
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Year: 2017
PMID： 28546319 DOI： 10.1136/oemed-2016-104248
Source DB: PubMed Journal: Occup Environ Med ISSN： 1351-0711 Impact factor: 4.402