Literature DB >> 2854615

The mechanism of ischemia-induced brain cell injury. The membrane theory.

K Kogure1, J Tanaka, T Araki.   

Abstract

Temporal ischemia of the brain injures only the selectively vulnerable brain cells. The dying process evolves along with glutamate-mediated intracellular signal-transduction system, together with a loss of Ca2+ homeostasis. Such post-ischemic changes eventually disrupt functional and structural integrity of the cell membrane and kill the neuron. Molecular basis in pharmacoprotective agents is discussed.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2854615     DOI： 10.1007/bf03160360

Source DB:  PubMed          Journal:  Neurochem Pathol        ISSN： 0734-600X


  7 in total

1.  Reduction of maturation phenomenon in cerebral ischemia with CDP-choline-loaded liposomes.

Authors:  M Fresta; G Puglisi
Journal:  Pharm Res       Date:  1999-12       Impact factor: 4.200

2.  Cerebellar superoxide dismutase expression in Menkes' kinky hair disease: an immunohistochemical investigation.

Authors:  N Shibata; A Hirano; M Kobayashi; T Umahara; T Kawanami; K Asayama
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088

Review 3.  Biochemical and molecular characteristics of the brain with developing cerebral infarction.

Authors:  H Kato; K Kogure
Journal:  Cell Mol Neurobiol       Date:  1999-02       Impact factor: 5.046

4.  Long-term changes in gerbil brain neurotransmitter receptors following transient cerebral ischaemia.

Authors:  T Araki; H Kato; K Kogure; Y Kanai
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

5.  Alteration of protein kinase C activity in the postischemic rat brain areas using in vitro [3H]phorbol 12,13-dibutyrate autoradiography.

Authors:  H Nagasawa; T Araki; K Kogure
Journal:  J Neural Transm Gen Sect       Date:  1993

6.  Delayed neuronal death and delayed neuronal recovery in the human brain following global ischemia.

Authors:  M Horn; W Schlote
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

7.  The vitamin-E analog trolox and the NMDA antagonist MK-801 protect pyramidal neurons in hippocampal slice cultures from IL-1beta-induced neurodegeneration.

Authors:  Ann-Cathrin Radesäter; Sara Johansson; Caroline Oberg; Johan Luthman
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.