Literature DB >> 28544046

Time-related changes in firing rates are influenced by recruitment threshold and twitch force potentiation in the first dorsal interosseous.

Jonathan D Miller1, Trent J Herda1, Michael A Trevino1, Adam J Sterczala1, Anthony B Ciccone1.   

Abstract

NEW
FINDINGS: What is the central question of this study? The influences of motor unit recruitment threshold and twitch force potentiation on the changes in firing rates during steady-force muscular contractions are not well understood. What is the main finding and its importance? The behaviour of motor units during steady force was influenced by recruitment threshold, such that firing rates decreased for lower-threshold motor units but increased for higher-threshold motor units. In addition, individuals with greater changes in firing rates possessed greater twitch force potentiation. There are contradictory reports regarding changes in motor unit firing rates during steady-force contractions. Inconsistencies are likely to be the result of previous studies disregarding motor unit recruitment thresholds and not examining firing rates on a subject-by-subject basis. It is hypothesized that firing rates are manipulated by twitch force potentiation during contractions. Therefore, in this study we examined time-related changes in firing rates at steady force in relationship to motor unit recruitment threshold in the first dorsal interosseous and the influence of twitch force potentiation on such changes in young versus aged individuals. Subjects performed a 12 s steady-force contraction at 50% maximal voluntary contraction, with evoked twitches before and after the contraction to quantify potentiation. Firing rates, in relationship to recruitment thresholds, were determined at the beginning, middle and end of the steady force. There were no firing rate changes for aged individuals. For the young, firing rates decreased slightly for lower-threshold motor units but increased for higher-threshold motor units. Twitch force potentiation was greater for young than aged subjects, and changes in firing rates were correlated with twitch force potentiation. Thus, individuals with greater increases in firing rates of higher-threshold motor units and decreases in lower-threshold motor units possessed greater twitch force potentiation. Overall, changes in firing rates during brief steady-force contractions are dependent on recruitment threshold and explained in part by twitch force potentiation. Given that firing rate changes were measured in relationship to recruitment threshold, this study illustrates a more complete view of firing rate changes during steady-force contractions.
© 2017 The Authors. Experimental Physiology © 2017 The Physiological Society.

Entities:  

Keywords:  aging; motor unit firing rate; potentiation

Mesh:

Year:  2017        PMID: 28544046     DOI: 10.1113/EP086262

Source DB:  PubMed          Journal:  Exp Physiol        ISSN: 0958-0670            Impact factor:   2.969


  5 in total

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4.  Method of analysis influences interpretations of sex-related differences in firing rates during prolonged submaximal isometric contractions.

Authors:  Hannah L Dimmick; Michael A Trevino; Jonathan D Miller; Mandy E Parra; Adam J Sterczala; Trent J Herda
Journal:  J Musculoskelet Neuronal Interact       Date:  2022-03-01       Impact factor: 1.864

5.  Characteristics of the Electrophysiological Properties of Neuromuscular Motor Units and Its Adaptive Strategy Response in Lower Extremity Muscles for Seniors with Pre-Sarcopenia: A Preliminary Study.

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  5 in total

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