Literature DB >> 28543771

Right ventricular pacemaker lead position is associated with differences in long-term outcomes and complications.

Chance M Witt1, Charles J Lenz1, Henry H Shih2, Elisa Ebrille1, Andrew N Rosenbaum1, Martin van Zyl2, Htin Aung1, Kevin K Manocha2, Abhishek J Deshmukh1, David O Hodge3, Siva K Mulpuru1, Yong-Mei Cha1, Raul E Espinosa1, Samuel J Asirvatham1, Christopher J Mcleod1.   

Abstract

INTRODUCTION: Cardiac pacing from the right ventricular apex is associated with detrimental long-term effects and nonapical pacing locations may be associated with improved outcomes. There is little data regarding complications with nonapical lead positions. The aim of this study was to assess long-term outcomes and lead-related complications associated with differing ventricular lead tip position. METHODS AND
RESULTS: All adult patients who underwent dual-chamber pacemaker implantation from 2004 to 2014 were included if they had postprocedure chest radiographs amenable to lead position determination. Long-term outcomes and lead-related complication rates were recorded. These were compared at 5 years between: (1) apical and septal leads, (2) apical and nonseptal nonapical (NSNA), and (3) apical and septal with >40% ventricular pacing. We retrospectively evaluated 3,450 patients, which included 238 with a septal position and 733 with NSNA lead positions. Septal lead position was associated with a lower mortality compared to apical leads (24% vs. 31%, P = 0.02). In patients with greater than 40% pacing, septal leads were associated with significantly higher rates of incident atrial fibrillation compared to apical leads (49% vs. 34%, P = 0.04). NSNA positions were associated with a significantly higher rate of lead dislodgement (4% vs. 2%, P = 0.005) and need for revision (8% vs. 5%, P = 0.005).
CONCLUSIONS: Septal pacemaker lead position is associated with a lower mortality compared to apically placed leads, but a higher incidence of atrial fibrillation with higher percentage ventricular pacing. NSNA lead locations are associated with more complications and should be avoided.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  atrial fibrillation; cardiomyopathy; complications; heart failure; mortality; ventricular pacing

Mesh:

Year:  2017        PMID: 28543771     DOI: 10.1111/jce.13256

Source DB:  PubMed          Journal:  J Cardiovasc Electrophysiol        ISSN: 1045-3873


  6 in total

1.  Association of selected factors with long-term prognosis and mortality after dual-chamber pacemaker implant.

Authors:  Maciej Dębski; Mateusz Ulman; Andrzej Ząbek; Krzysztof Boczar; Kazimierz Haberka; Marcin Kuniewicz; Jacek Lelakowski; Barbara Małecka
Journal:  Cardiol J       Date:  2018-08-29       Impact factor: 2.737

2.  Paced QRS morphology and outcomes.

Authors:  Richard Sutton
Journal:  Indian Pacing Electrophysiol J       Date:  2019-03-08

3.  Paced QRS morphology predicts incident left ventricular systolic dysfunction and atrial fibrillation.

Authors:  Martin van Zyl; Chance M Witt; Subir Bhatia; Majd Khasawneh; Prakriti Gaba; Charles J Lenz; Andrew N Rosenbaum; Htin Aung; David O Hodge; Christopher J McLeod; Samuel J Asirvatham
Journal:  Indian Pacing Electrophysiol J       Date:  2019-03-08

4.  Assessing safety of leadless pacemaker (MICRA) at various implantation sites and its impact on paced QRS in Indian population.

Authors:  Prafull Sharma; Vivek Singh Guleria; Prashant Bharadwaj; Rajat Datta
Journal:  Indian Heart J       Date:  2020-08-10

5.  Echocardiographic Predictors of All-Cause Mortality in Patients with Hypertrophic Cardiomyopathy following Pacemaker Implantation.

Authors:  Nixiao Zhang; Wei Hua; Xiaoping Li; Yiran Hu; Hongxia Niu; Chi Cai; Min Gu; Xuhua Chen; Shu Zhang
Journal:  Cardiol Res Pract       Date:  2020-02-14       Impact factor: 1.866

6.  Feasibility study for echocardiography-guided lead insertion for permanent cardiac implantable electronic devices.

Authors:  Omolade O Sogade; Rieta N Aben; Harry Eyituoyo; Nkechi C Arinze; Felix O Sogade
Journal:  Pacing Clin Electrophysiol       Date:  2021-07-18       Impact factor: 1.976

  6 in total

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