Literature DB >> 28543168

A New Tool to Tackle the Opioid Epidemic: Description, Utility, and Results from the Maine Diversion Alert Program.

Brian J Piper1,2, Clare E Desrosiers3, Harriet C Fisher4, Kenneth L McCall5, Stephanie D Nichols6,7,8.   

Abstract

STUDY
OBJECTIVE: The opioid epidemic continues to impact the United States, and new strategies are needed to combat this epidemic. The objective of this study was to analyze 2015 drug arrest data from Maine's Diversion Alert (DA) program (diversionalert.org), compare arrest data between the first quarters of 2015 and 2016, and provide an analysis of the sex differences in the arrests as well as information about DA use. STUDY
DESIGN: This was a population-based descriptive study using data from the Maine DA program. The study population consisted of persons arrested for prescription, nonprescription, or illicit drugs. DATA SOURCE: DA database.
MEASUREMENTS AND MAIN RESULTS: The DA program addresses Maine's prescription drug abuse epidemic with innovative resources that provide access to drug arrest data for health care providers to identify and respond to patients at risk for overdose, those engaged in illegal prescription drug distribution, and those who need treatment. Drug arrest data from 2015 (2723 arrests) and the first quarter of 2016 (788 arrests) were compared and analyzed. The drugs implicated in the arrests were organized by Drug Enforcement Agency (DEA) schedule category and whether they were pharmaceuticals (synthesized and distributed by a pharmaceutical company) or nonpharmaceuticals (grown or synthesized in clandestine laboratories). Most arrests were for possession (64.5%) followed by trafficking (23.8%). Heroin was listed in more than three-quarters (76.4%) of the Schedule I arrests, followed by marijuana (11.7%) and "bath salts" (6.3%). Cocaine and crack cocaine were implicated in almost half (46.7%) of the Schedule II arrests, followed by oxycodone (21.0%) and methamphetamine/amphetamine (15.8%). Buprenorphine was responsible for almost all (96.7%) of the Schedule III arrests. The benzodiazepines alprazolam (34.3%), clonazepam (33.8%), diazepam (11.9%), and lorazepam (8.5%) were listed in the preponderance of the Schedule IV arrests. Arrests increased in 2016 by 49.2% for heroin (p<0.01) and 170.0% for methamphetamine (p≤0.0005) relative to 2015. Arrests for trafficking increased by 42.9% (p<0.05). Males outnumbered females 2:1 in DA. Schedule IV agents accounted for only 6.8% of arrests for males versus 11.5% for females (p≤0.0001). Conversely, Schedule I agents were implicated in 33.0% of arrests for males versus only 27.3% for females (p<0.005).
CONCLUSION: DA is an important tool for providing timely information for health care providers regarding individuals with a history of past misuse of psychotherapeutic agents, particularly opioids and stimulants.
© 2017 Pharmacotherapy Publications, Inc.

Entities:  

Keywords:  Diversion Alert; Maine; buprenorphine; cocaine; crime; heroin; opioid; oxycodone

Mesh:

Substances:

Year:  2017        PMID: 28543168      PMCID: PMC5693423          DOI: 10.1002/phar.1952

Source DB:  PubMed          Journal:  Pharmacotherapy        ISSN: 0277-0008            Impact factor:   4.705


  19 in total

Review 1.  What we know, and don't know, about the impact of state policy and systems-level interventions on prescription drug overdose.

Authors:  Tamara M Haegerich; Leonard J Paulozzi; Brian J Manns; Christopher M Jones
Journal:  Drug Alcohol Depend       Date:  2014-10-14       Impact factor: 4.492

2.  Factors contributing to the rise of buprenorphine misuse: 2008-2013.

Authors:  Theodore J Cicero; Matthew S Ellis; Hilary L Surratt; Steven P Kurtz
Journal:  Drug Alcohol Depend       Date:  2014-06-18       Impact factor: 4.492

3.  Prescription Monitoring Program Trends Among Individuals Arrested in Maine for Trafficking Prescription Drugs in 2014.

Authors:  Kenneth McCall; Stephanie D Nichols; Christina Holt; Leslie Ochs; Gary Cattabriga; Chunhao Tu
Journal:  Pharmacotherapy       Date:  2016-06       Impact factor: 4.705

4.  Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers - United States, 2002-2004 and 2008-2010.

Authors:  Christopher M Jones
Journal:  Drug Alcohol Depend       Date:  2013-02-12       Impact factor: 4.492

Review 5.  Medication-related falls in the elderly: causative factors and preventive strategies.

Authors:  Allen R Huang; Louise Mallet; Christian M Rochefort; Tewodros Eguale; David L Buckeridge; Robyn Tamblyn
Journal:  Drugs Aging       Date:  2012-05-01       Impact factor: 3.923

6.  Single dose pharmacokinetics and pharmacodynamics of oral loprazolam in the elderly.

Authors:  C G Swift; M R Swift; S I Ankier; A Pidgen; J Robinson
Journal:  Br J Clin Pharmacol       Date:  1985-08       Impact factor: 4.335

7.  HIV Infection Linked to Injection Use of Oxymorphone in Indiana, 2014-2015.

Authors:  Philip J Peters; Pamela Pontones; Karen W Hoover; Monita R Patel; Romeo R Galang; Jessica Shields; Sara J Blosser; Michael W Spiller; Brittany Combs; William M Switzer; Caitlin Conrad; Jessica Gentry; Yury Khudyakov; Dorothy Waterhouse; S Michele Owen; Erika Chapman; Jeremy C Roseberry; Veronica McCants; Paul J Weidle; Dita Broz; Taraz Samandari; Jonathan Mermin; Jennifer Walthall; John T Brooks; Joan M Duwve
Journal:  N Engl J Med       Date:  2016-07-21       Impact factor: 91.245

Review 8.  Benzodiazepine poisoning. Clinical and pharmacological considerations and treatment.

Authors:  P Gaudreault; J Guay; R L Thivierge; I Verdy
Journal:  Drug Saf       Date:  1991 Jul-Aug       Impact factor: 5.606

Review 9.  Gabapentin misuse, abuse and diversion: a systematic review.

Authors:  Rachel V Smith; Jennifer R Havens; Sharon L Walsh
Journal:  Addiction       Date:  2016-03-18       Impact factor: 6.526

10.  Diversion Alert: 1-Year Evaluation Across Northern New England, 2013-2014.

Authors:  Sarah Levin Martin; Clare Desrosiers
Journal:  Prev Chronic Dis       Date:  2016-11-23       Impact factor: 2.830

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  2 in total

1.  Epidemiology of HIV, Sexually Transmitted Infections, Viral Hepatitis, and Tuberculosis Among Incarcerated Transgender People: A Case of Limited Data.

Authors:  Tonia C Poteat; Mannat Malik; Chris Beyrer
Journal:  Epidemiol Rev       Date:  2018-06-01       Impact factor: 6.222

2.  Descriptive, observational study of pharmaceutical and non-pharmaceutical arrests, use, and overdoses in Maine.

Authors:  Kevin J Simpson; Matthew T Moran; Michelle L Foster; Dipam T Shah; Daniel Y Chung; Stephanie D Nichols; Kenneth L McCall; Brian J Piper
Journal:  BMJ Open       Date:  2019-04-29       Impact factor: 2.692

  2 in total

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