| Literature DB >> 28539779 |
Panitha Jindahra1,2, T Plant1,2.
Abstract
Neuromyelitis optica or Devic disease is an inflammatory disorder of the central nervous system. It is caused by antibodies that attack aquaporin 4 water channels in the cell membrane of astrocytic foot processes at the blood brain barrier. It can involve the optic nerve, the spinal cord and beyond. Here we review its pathophysiology, clinical features, and therapy.Entities:
Keywords: Devic disease; NMO spectrum disorders; NMO-IgG; Neuromyelitis optica; optic neuritis; transverse myelitis
Year: 2012 PMID: 28539779 PMCID: PMC5436187 DOI: 10.2147/EB.S8392
Source DB: PubMed Journal: Eye Brain ISSN: 1179-2744