| Literature DB >> 2853951 |
M Gody1, S A Ouattara, G de Thé.
Abstract
A dramatic rise in AIDS cases in a rural hospital 60 km west of Abidjan is described. Out of 212 adult cases diagnosed between January and November 1987 as having AIDS, using the World Health Organization (WHO) criteria defined in Bangui, 128 (60%) had antibodies to HIV-1 only, 61 (29%) had antibodies to both HIV-1 and HIV-2, 15 (7%) had antibodies to HIV-2 only and eight (4%) had no detectable antibodies to HIVs. These results, taken together with those of Ouattara et al. showing that both retroviruses have a similar seroprevalence in the general rural and urban populations, suggest that HIV-2 may have a lower physiopathological potential than HIV-1. This suggestion is supported by a 6-month follow-up of 60 AIDS cases, but only longer follow-up of cohorts of patients and healthy subjects with antibodies to one of the two viruses will allow definitive conclusions.Entities:
Keywords: Acquired Immunodeficiency Syndrome--changes; Adult; Africa; Africa South Of The Sahara; Age Factors; Clinical Research; Demographic Factors; Developing Countries; Diseases; French Speaking Africa; Hiv Infections; Ivory Coast; Longterm Effects; Measurement; Population; Population Characteristics; Population Dynamics; Prevalence; Research Methodology; Signs And Symptoms; Time Factors; Viral Diseases; Western Africa
Mesh：
Year: 1988 PMID： 2853951 DOI： 10.1097/00002030-198812000-00004
Source DB: PubMed Journal: AIDS ISSN： 0269-9370 Impact factor: 4.177