Literature DB >> 28539062

Two new flavonoids from Artemisia argyi with their anticoagulation activities.

Jie-Li Lv1, Zhen-Zhen Li1, Lai-Bin Zhang1.   

Abstract

A new flavone glycoside, eupatilin 7-O-β-d-glucopyranoside (1) and a new flavone, 5,6,2',4'-tetrahydroxy-7,5'-dimethoxyflavone (2), were isolated from Artemisia argyi. Their structures were unambiguously elucidated by extensive spectroscopic analysis. Both flavonoids were evaluated for in vitro anticoagulation activities. Compound 1 significantly extended thrombin time. Compound 2 had obvious effect in increasing prothrombin time.

Entities:  

Keywords:  Artemisia argyi; Compositae; anticoagulation activity; flavone

Mesh：

Substances：

Year:  2017        PMID： 28539062     DOI： 10.1080/14786419.2017.1332603

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  5 in total

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Journal:  Front Microbiol       Date:  2022-06-23       Impact factor: 6.064

2.  Artemisia princeps Inhibits Adipogenic Differentiation of 3T3-L1 Pre-Adipocytes via Downregulation of PPARγ and MAPK Pathways.

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4.  Genome sequencing reveals chromosome fusion and extensive expansion of genes related to secondary metabolism in Artemisia argyi.

Authors:  Yuhuan Miao; Dandan Luo; Tingting Zhao; Hongzhi Du; Zhenhua Liu; Zhongping Xu; Lanping Guo; Changjie Chen; Sainan Peng; Jin Xin Li; Lin Ma; Guogui Ning; Dahui Liu; Luqi Huang
Journal:  Plant Biotechnol J       Date:  2022-07-11       Impact factor: 13.263

5.  Study on Structure Activity Relationship of Natural Flavonoids against Thrombin by Molecular Docking Virtual Screening Combined with Activity Evaluation In Vitro.

Authors:  Xiaoyan Wang; Zhen Yang; Feifei Su; Jin Li; Evans Owusu Boadi; Yan-Xu Chang; Hui Wang
Journal:  Molecules       Date:  2020-01-20       Impact factor: 4.411
  5 in total

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