Jay Siak1, Mirna Kumaradas2, Soon-Phaik Chee1,3,4. 1. a Singapore National Eye Centre , Singapore Eye Research Institute , Singapore. 2. b Mediclinic Hospital , Colombo , Sri Lanka. 3. c Department of Ophthalmology, Yong Loo Lin School of Medicine , National University of Singapore , Singapore. 4. d Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Medical School , Singapore.
Abstract
PURPOSE: To describe the pattern of uveitis at a tertiary uveitis referral clinic in Sri Lanka. METHODS: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed. RESULTS: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). 485 (65%) were idiopathic. The top identified causes of AU were seronegative-spondyloarthropathy-related-AU (37, 13%), HLA-B27-related-AU without systemic associations (25, 9%), herpetic-AU (18, 6%), and trematode uveitis (8, 3%). The main posterior uveitis were toxoplasmosis (34, 18%), tuberculosis (21, 11%), and sarcoidosis (17, 9%). 78% of intermediate uveitis were idiopathic, with 12 (8%) tuberculosis, and 10 (7%) sarcoidosis. The most common panuveitis were sarcoidosis (18, 14%), tuberculosis (14, 11%), and Vogt-Koyanagi-Harada disease (10, 8%). Among children (≤12 years) accounting for 25 (3%) of cases, the most common presentations were idiopathic intermediate uveitis (7, 28%), idiopathic-AU (4, 16%), toxoplasmosis (4, 16%), trematode uveitis (3, 12%), and toxocariasis (2, 8%). CONCLUSIONS: An infectious etiology must be considered in posterior uveitis and uveitis among children in the Sri Lankan population.
PURPOSE: To describe the pattern of uveitis at a tertiary uveitis referral clinic in Sri Lanka. METHODS: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed. RESULTS: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). 485 (65%) were idiopathic. The top identified causes of AU were seronegative-spondyloarthropathy-related-AU (37, 13%), HLA-B27-related-AU without systemic associations (25, 9%), herpetic-AU (18, 6%), and trematode uveitis (8, 3%). The main posterior uveitis were toxoplasmosis (34, 18%), tuberculosis (21, 11%), and sarcoidosis (17, 9%). 78% of intermediate uveitis were idiopathic, with 12 (8%) tuberculosis, and 10 (7%) sarcoidosis. The most common panuveitis were sarcoidosis (18, 14%), tuberculosis (14, 11%), and Vogt-Koyanagi-Harada disease (10, 8%). Among children (≤12 years) accounting for 25 (3%) of cases, the most common presentations were idiopathic intermediate uveitis (7, 28%), idiopathic-AU (4, 16%), toxoplasmosis (4, 16%), trematode uveitis (3, 12%), and toxocariasis (2, 8%). CONCLUSIONS: An infectious etiology must be considered in posterior uveitis and uveitis among children in the Sri Lankan population.
Entities:
Keywords:
Asia; Sri Lanka; epidemiology; infection; uveitis
Authors: Doan Luong Hien; Neil Onghanseng; Than Trong Tuong Ngoc; Jaclyn Joyce Hwang; Brandon Huy Pham; Huy Luong Doan; Huy V Nguyen; Muhammad Sohail Halim; Gunay Uludag; Yasir J Sepah; Diana V Do; Quan Dong Nguyen Journal: Am J Ophthalmol Case Rep Date: 2020-07-11