Literature DB >> 28535683

Electrocatalytic C-H/N-H Coupling of 2'-Aminoacetophenones for the Synthesis of Isatins.

Peng Qian1, Ji-Hu Su1, Yukang Wang1, Meixiang Bi1, Zhenggen Zha1, Zhiyong Wang1.   

Abstract

2'-Aminoacetophenones undergo a C(sp3)-H oxidation followed by intramolecular C-N bond formation by virtue of a simple electrochemical oxidation in the presence of n-Bu4NI, providing various isatins with moderate to good yields. The reaction intermediates were detected, and a radical-based pathway was proposed.

Entities:  

Year:  2017        PMID： 28535683     DOI： 10.1021/acs.joc.7b00635

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance.

Authors:  Ming Yan; Yu Kawamata; Phil S Baran
Journal:  Chem Rev       Date:  2017-10-09       Impact factor: 60.622

Review 2.  Electrifying Organic Synthesis.

Authors:  Anton Wiebe; Tile Gieshoff; Sabine Möhle; Eduardo Rodrigo; Michael Zirbes; Siegfried R Waldvogel
Journal:  Angew Chem Int Ed Engl       Date:  2018-03-07       Impact factor: 15.336

3.  Stereoselective synthesis of sulfur-containing β-enaminonitrile derivatives through electrochemical Csp3-H bond oxidative functionalization of acetonitrile.

Authors:  Tian-Jun He; Zongren Ye; Zhuofeng Ke; Jing-Mei Huang
Journal:  Nat Commun       Date:  2019-02-19       Impact factor: 14.919

4.  Electrosynthesis of Quinazolines and Quinazolinones via an Anodic Direct Oxidation C(sp3)-H Amination/C-N Cleavage of Tertiary Amine in Aqueous Medium.

Authors:  Zhenghong Zhou; Kangfei Hu; Jiawei Wang; Zhibin Li; Yan Zhang; Zhenggen Zha; Zhiyong Wang
Journal:  ACS Omega       Date:  2020-12-01

5.  Stereoselective Synthesis of Spiro-Decalin Oxindole Derivatives via Sequential Organocatalytic Michael-Domino Michael/Aldol Reaction.

Authors:  Leonardo Straminelli; Francesco Vicentini; Antonio Di Sabato; Carmela Maria Montone; Chiara Cavaliere; Kari Rissanen; Francesca Leonelli; Fabrizio Vetica
Journal:  J Org Chem       Date:  2022-07-25       Impact factor: 4.198

6.  Synergistic Effect over Sub-nm Pt Nanocluster@MOFs Significantly Boosts Photo-oxidation of N-alkyl(iso)quinolinium Salts.

Authors:  Shan-Shan Fu; Xiu-Ying Ren; Song Guo; Guangxu Lan; Zhi-Ming Zhang; Tong-Bu Lu; Wenbin Lin
Journal:  iScience       Date:  2019-12-23
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.