Literature DB >> 2853361

Tumor necrosis factor: a plurifunctional mediator of acute inflammation.

J S Warren1, P A Ward, K J Johnson.   

Abstract

In recent years intense research activity has been directed toward characterizing polypeptide mediators that regulate growth, differentiation, and function of cells involved in inflammation, immunity, and hematopoiesis. Tumor necrosis factor (TNF), or cachectin, is one of these cytokines. This review will summarize important observations that have led to our current definition of TNF. The relationship of TNF to other cytokines and basic TNF biology are discussed. Particular attention is directed toward the evidence which implicates TNF as an important mediator of acute inflammation.

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Year:  1988        PMID: 2853361

Source DB:  PubMed          Journal:  Mod Pathol        ISSN: 0893-3952            Impact factor:   7.842


  9 in total

1.  Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Chen et C. Ling and Scutellaria baicalensis Georgi.

Authors:  Jue Zhou; Fan Qu; Hang-Jun Zhang; Xiao-Hong Zhuge; Liang-Zhong Cheng
Journal:  Afr J Tradit Complement Altern Med       Date:  2010-07-03

2.  The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor-alpha and leukotriene B4 in a novel human whole blood assay.

Authors:  C Brideau; C Van Staden; A Styhler; I W Rodger; C C Chan
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

3.  Effects of forskolin on Kupffer cell production of interleukin-10 and tumor necrosis factor alpha differ from those of endogenous adenylyl cyclase activators: possible role for adenylyl cyclase 9.

Authors:  Maria K Dahle; Anders E Myhre; Ansgar O Aasen; Jacob E Wang
Journal:  Infect Immun       Date:  2005-11       Impact factor: 3.441

4.  CD47 Binding on Vascular Endothelial Cells Inhibits IL-17-Mediated Leukocyte Adhesion.

Authors:  Laura Soriano-Romaní; Fayaz A Mir; Niharika Singh; Ian Chin; Ali Hafezi-Moghadam; Sharmila Masli
Journal:  Int J Mol Sci       Date:  2022-05-20       Impact factor: 6.208

5.  The membrane attack complex of complement induces interleukin-8 and monocyte chemoattractant protein-1 secretion from human umbilical vein endothelial cells.

Authors:  K S Kilgore; C M Flory; B F Miller; V M Evans; J S Warren
Journal:  Am J Pathol       Date:  1996-09       Impact factor: 4.307

6.  Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept.

Authors:  E Mazzon; E Esposito; R Di Paola; C Muià; C Crisafulli; T Genovese; R Caminiti; R Meli; P Bramanti; S Cuzzocrea
Journal:  Clin Exp Immunol       Date:  2008-05-26       Impact factor: 4.330

7.  Cytokine secretion by genetically modified nonimmunogenic murine fibrosarcoma. Tumor inhibition by IL-2 but not tumor necrosis factor.

Authors:  S E Karp; A Farber; J C Salo; P Hwu; G Jaffe; A L Asher; E Shiloni; N P Restifo; J J Mulé; S A Rosenberg
Journal:  J Immunol       Date:  1993-02-01       Impact factor: 5.422

8.  Antibacterial and anti-inflammatory activities of an extract, fractions, and compounds isolated from Gochnatia pulchra aerial parts.

Authors:  R Lucarini; M G Tozatti; M L A Silva; V M M Gimenez; P M Pauletti; M Groppo; I C C Turatti; W R Cunha; C H G Martins
Journal:  Braz J Med Biol Res       Date:  2015-07-21       Impact factor: 2.590

9.  Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation.

Authors:  Emanuela Mazzon; Salvatore Cuzzocrea
Journal:  Respir Res       Date:  2007-10-30
  9 in total

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