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Literature DB >> 28532654

Flexible IgE epitope-containing domains of Phl p 5 cause high allergenic activity.

Christoph Göbl¹, Margarete Focke-Tejkl², Nazanin Najafi², Evelyne Schrank³, Tobias Madl⁴, Simone Kosol³, Christoph Madritsch², Yulia Dorofeeva², Sabine Flicker², Josef Thalhamer⁵, Rudolf Valenta⁶, Klaus Zangger⁷, Nico Tjandra⁸.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2017 PMID： 28532654 PMCID： PMC5632575 DOI： 10.1016/j.jaci.2017.05.005

Source DB: PubMed Journal: J Allergy Clin Immunol ISSN： 0091-6749 Impact factor: 10.793

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9 in total

1. Crystallization and preliminary diffraction data of a major pollen allergen. Crystal growth separates a low molecular weight form with elevated biological activity.

Authors: A Bufe; C Betzel; G Schramm; A Petersen; W M Becker; M Schlaak; M Perbandt; Z Dauter; W Weber
Journal: J Biol Chem Date: 1996-11-01 Impact factor: 5.157

2. A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain.

Authors: S Flicker; S Vrtala; P Steinberger; L Vangelista; A Bufe; A Petersen; M Ghannadan; W R Sperr; P Valent; L Norderhaug; B Bohle; H Stockinger; C Suphioglu; E K Ong; D Kraft; R Valenta
Journal: J Immunol Date: 2000-10-01 Impact factor: 5.422

3. cDNA cloning of a major allergen from timothy grass (Phleum pratense) pollen; characterization of the recombinant Phl pV allergen.

Authors: S Vrtala; W R Sperr; I Reimitzer; R van Ree; S Laffer; W D Müller; P Valent; K Lechner; H Rumpold; D Kraft
Journal: J Immunol Date: 1993-11-01 Impact factor: 5.422

4. Structure of the functional domain of the major grass-pollen allergen Phlp 5b.

Authors: Kanagalaghatta Rajashankar; Albrecht Bufe; Wolfgang Weber; Susanne Eschenburg; Buko Lindner; Christian Betzel
Journal: Acta Crystallogr D Biol Crystallogr Date: 2002-06-20

5. A major IgE epitope-containing grass pollen allergen domain from Phl p 5 folds as a four-helix bundle.

Authors: Ornella Maglio; Jose W Saldanha; Susanne Vrtala; Susanne Spitzauer; Rudolf Valenta; Annalisa Pastore
Journal: Protein Eng Date: 2002-08

6. Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.

Authors: Margarete Focke-Tejkl; Milena Weber; Katarzyna Niespodziana; Angela Neubauer; Hans Huber; Rainer Henning; Gottfried Stegfellner; Bernhard Maderegger; Martina Hauer; Frank Stolz; Verena Niederberger; Katharina Marth; Julia Eckl-Dorna; Richard Weiss; Josef Thalhamer; Katharina Blatt; Peter Valent; Rudolf Valenta
Journal: J Allergy Clin Immunol Date: 2014-11-13 Impact factor: 10.793

7. IgE epitope proximity determines immune complex shape and effector cell activation capacity.

Authors: Anna Gieras; Birgit Linhart; Kenneth H Roux; Moumita Dutta; Marat Khodoun; Domen Zafred; Clarissa R Cabauatan; Christian Lupinek; Milena Weber; Margarete Focke-Tejkl; Walter Keller; Fred D Finkelman; Rudolf Valenta
Journal: J Allergy Clin Immunol Date: 2015-12-10 Impact factor: 10.793

8. Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5.

Authors: Margarete Focke-Tejkl; Raffaela Campana; Renate Reininger; Christian Lupinek; Katharina Blatt; Peter Valent; Tea Pavkov-Keller; Walter Keller; Rudolf Valenta
Journal: J Allergy Clin Immunol Date: 2013-10-31 Impact factor: 10.793

9. Mechanisms, safety and efficacy of a B cell epitope-based vaccine for immunotherapy of grass pollen allergy.

Authors: Petra Zieglmayer; Margarete Focke-Tejkl; René Schmutz; Patrick Lemell; René Zieglmayer; Milena Weber; Renata Kiss; Katharina Blatt; Peter Valent; Frank Stolz; Hans Huber; Angela Neubauer; Anette Knoll; Friedrich Horak; Rainer Henning; Rudolf Valenta
Journal: EBioMedicine Date: 2016-08-20 Impact factor: 8.143

9 in total

1. Linear Epitope Binding Patterns of Grass Pollen-Specific Antibodies in Allergy and in Response to Allergen-Specific Immunotherapy.

Authors: Linnea Thörnqvist; Ronald Sjöberg; Lennart Greiff; Marianne van Hage; Mats Ohlin
Journal: Front Allergy Date: 2022-03-31

Review 2. How Do Pollen Allergens Sensitize?

Authors: Svetlana V Guryanova; Ekaterina I Finkina; Daria N Melnikova; Ivan V Bogdanov; Barbara Bohle; Tatiana V Ovchinnikova
Journal: Front Mol Biosci Date: 2022-06-16

3. Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.

Authors: J M Orengo; A R Radin; V Kamat; A Badithe; L H Ben; B L Bennett; S Zhong; D Birchard; A Limnander; A Rafique; J Bautista; A Kostic; D Newell; X Duan; M C Franklin; W Olson; T Huang; N A Gandhi; L Lipsich; N Stahl; N J Papadopoulos; A J Murphy; G D Yancopoulos
Journal: Nat Commun Date: 2018-04-12 Impact factor: 14.919

4. A robust method for the estimation and visualization of IgE cross-reactivity likelihood between allergens belonging to the same protein family.

Authors: Maksymilian Chruszcz; A Brenda Kapingidza; Coleman Dolamore; Krzysztof Kowal
Journal: PLoS One Date: 2018-11-29 Impact factor: 3.240