Literature DB >> 28530113

Refining Current Scientific Priorities and Identifying New Scientific Gaps in HIV-Related Heart, Lung, Blood, and Sleep Research.

Homer L Twigg1, Ronald Crystal2, Judith Currier3, Paul Ridker4, Nancy Berliner4, Hans-Peter Kiem5, George Rutherford6, Shimian Zou7, Simone Glynn7, Renee Wong7, Emmanuel Peprah7, Michael Engelgau7, Tony Creazzo7, Sandra Colombini-Hatch7, Elisabet Caler7.   

Abstract

The National Heart, Lung, and Blood Institute (NHLBI) AIDS Program's goal is to provide direction and support for research and training programs in areas of HIV-related heart, lung, blood, and sleep (HLBS) diseases. To better define NHLBI current HIV-related scientific priorities and with the goal of identifying new scientific priorities and gaps in HIV-related HLBS research, a wide group of investigators gathered for a scientific NHLBI HIV Working Group on December 14-15, 2015, in Bethesda, MD. The core objectives of the Working Group included discussions on: (1) HIV-related HLBS comorbidities in the antiretroviral era; (2) HIV cure; (3) HIV prevention; and (4) mechanisms to implement new scientific discoveries in an efficient and timely manner so as to have the most impact on people living with HIV. The 2015 Working Group represented an opportunity for the NHLBI to obtain expert advice on HIV/AIDS scientific priorities and approaches over the next decade.

Entities:  

Keywords:  HIV epidemiology; HIV/AIDS pathogenesis; implementation science

Mesh:

Year:  2017        PMID: 28530113      PMCID: PMC5583565          DOI: 10.1089/AID.2017.0026

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN: 0889-2229            Impact factor:   2.205


  69 in total

Review 1.  Prophylaxis against opportunistic infections in patients with human immunodeficiency virus infection.

Authors:  J A Kovacs; H Masur
Journal:  N Engl J Med       Date:  2000-05-11       Impact factor: 91.245

2.  Impact of combination therapy for HIV infection on inpatient census.

Authors:  R A Torres; M Barr
Journal:  N Engl J Med       Date:  1997-05-22       Impact factor: 91.245

3.  Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial.

Authors:  Thomas A Rasmussen; Martin Tolstrup; Christel R Brinkmann; Rikke Olesen; Christian Erikstrup; Ajantha Solomon; Anni Winckelmann; Sarah Palmer; Charles Dinarello; Maria Buzon; Mathias Lichterfeld; Sharon R Lewin; Lars Østergaard; Ole S Søgaard
Journal:  Lancet HIV       Date:  2014-09-15       Impact factor: 12.767

4.  Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.

Authors:  Vivek Jain; Wendy Hartogensis; Peter Bacchetti; Peter W Hunt; Hiroyu Hatano; Elizabeth Sinclair; Lorrie Epling; Tzong-Hae Lee; Michael P Busch; Joseph M McCune; Christopher D Pilcher; Frederick M Hecht; Steven G Deeks
Journal:  J Infect Dis       Date:  2013-07-12       Impact factor: 5.226

5.  Inflammatory cytokines drive CD4+ T-cell cycling and impaired responsiveness to interleukin 7: implications for immune failure in HIV disease.

Authors:  Carey L Shive; Joseph C Mudd; Nicholas T Funderburg; Scott F Sieg; Benjamin Kyi; Doug A Bazdar; Davide Mangioni; Andrea Gori; Jeffrey M Jacobson; Ari D Brooks; Jeffrey Hardacre; John Ammori; Jacob D Estes; Timothy W Schacker; Benigno Rodriguez; Michael M Lederman
Journal:  J Infect Dis       Date:  2014-02-28       Impact factor: 5.226

6.  Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV.

Authors:  Pablo Tebas; David Stein; Winson W Tang; Ian Frank; Shelley Q Wang; Gary Lee; S Kaye Spratt; Richard T Surosky; Martin A Giedlin; Geoff Nichol; Michael C Holmes; Philip D Gregory; Dale G Ando; Michael Kalos; Ronald G Collman; Gwendolyn Binder-Scholl; Gabriela Plesa; Wei-Ting Hwang; Bruce L Levine; Carl H June
Journal:  N Engl J Med       Date:  2014-03-06       Impact factor: 91.245

Review 7.  Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions.

Authors:  Julie C Gaardbo; Hans J Hartling; Jan Gerstoft; Susanne D Nielsen
Journal:  Clin Dev Immunol       Date:  2012-03-14

8.  HIV infection and HIV-associated behaviors among persons who inject drugs--20 cities, United States, 2012.

Authors:  Michael W Spiller; Dita Broz; Cyprian Wejnert; Lina Nerlander; Gabriela Paz-Bailey
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2015-03-20       Impact factor: 17.586

9.  Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.

Authors:  Julian H Elliott; Fiona Wightman; Ajantha Solomon; Khader Ghneim; Jeffrey Ahlers; Mark J Cameron; Miranda Z Smith; Tim Spelman; James McMahon; Pushparaj Velayudham; Gregor Brown; Janine Roney; Jo Watson; Miles H Prince; Jennifer F Hoy; Nicolas Chomont; Rémi Fromentin; Francesco A Procopio; Joumana Zeidan; Sarah Palmer; Lina Odevall; Ricky W Johnstone; Ben P Martin; Elizabeth Sinclair; Steven G Deeks; Daria J Hazuda; Paul U Cameron; Rafick-Pierre Sékaly; Sharon R Lewin
Journal:  PLoS Pathog       Date:  2014-11-13       Impact factor: 6.823

Review 10.  Platelets and infection - an emerging role of platelets in viral infection.

Authors:  Alice Assinger
Journal:  Front Immunol       Date:  2014-12-18       Impact factor: 7.561

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  2 in total

1.  Cardiovascular Disease Prevention Education Using a Virtual Environment in Sexual-Minority Men of Color With HIV: Protocol for a Sequential, Mixed Method, Waitlist Randomized Controlled Trial.

Authors:  S Raquel Ramos; Constance Johnson; Gail Melkus; Trace Kershaw; Marya Gwadz; Harmony Reynolds; Allison Vorderstrasse
Journal:  JMIR Res Protoc       Date:  2022-05-17

2.  Classical monocyte transcriptomes reveal significant anti-inflammatory statin effect in women with chronic HIV.

Authors:  Erik Ehinger; Yanal Ghosheh; Akula Bala Pramod; Juan Lin; David B Hanna; Karin Mueller; Christopher P Durant; Livia Baas; Qibin Qi; Tao Wang; Konrad Buscher; Kathryn Anastos; Jason M Lazar; Wendy J Mack; Phyllis C Tien; Mardge H Cohen; Igho Ofotokun; Stephen Gange; Sonya L Heath; Howard N Hodis; Russell P Tracy; Alan L Landay; Robert C Kaplan; Klaus Ley
Journal:  Cardiovasc Res       Date:  2021-03-21       Impact factor: 13.081

  2 in total

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