Literature DB >> 28529309

An unusual, activating insertion/deletion MPL mutant in primary myelofibrosis.

J-P Defour1,2,3, Y Hoade4,5, A-M Reuther4, A Callaway4, D Ward4, F Chen6, S N Constantinescu1,2, N C P Cross4,5.   

Abstract

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Year:  2017        PMID： 28529309     DOI： 10.1038/leu.2017.153

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  9 in total

1.  Orientation-specific signalling by thrombopoietin receptor dimers.

Authors:  Judith Staerk; Jean-Philippe Defour; Christian Pecquet; Emilie Leroy; Hélène Antoine-Poirel; Ian Brett; Miki Itaya; Steven O Smith; William Vainchenker; Stefan N Constantinescu
Journal:  EMBO J       Date:  2011-09-02       Impact factor: 11.598

Review 2.  Genomics of Myeloproliferative Neoplasms.

Authors:  Katerina Zoi; Nicholas C P Cross
Journal:  J Clin Oncol       Date:  2017-02-13       Impact factor: 44.544

3.  Oncogenic activation of MPL/thrombopoietin receptor by 17 mutations at W515: implications for myeloproliferative neoplasms.

Authors:  J-P Defour; I Chachoua; C Pecquet; S N Constantinescu
Journal:  Leukemia       Date:  2015-10-06       Impact factor: 11.528

4.  Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms.

Authors:  Jelena D Milosevic Feenstra; Harini Nivarthi; Heinz Gisslinger; Emilie Leroy; Elisa Rumi; Ilyas Chachoua; Klaudia Bagienski; Blanka Kubesova; Daniela Pietra; Bettina Gisslinger; Chiara Milanesi; Roland Jäger; Doris Chen; Tiina Berg; Martin Schalling; Michael Schuster; Christoph Bock; Stefan N Constantinescu; Mario Cazzola; Robert Kralovics
Journal:  Blood       Date:  2015-09-30       Impact factor: 22.113

5.  His499 Regulates Dimerization and Prevents Oncogenic Activation by Asparagine Mutations of the Human Thrombopoietin Receptor.

Authors:  Emilie Leroy; Jean-Philippe Defour; Takeshi Sato; Sharmila Dass; Vitalina Gryshkova; Myat M Shwe; Judith Staerk; Stefan N Constantinescu; Steven O Smith
Journal:  J Biol Chem       Date:  2015-12-01       Impact factor: 5.157

6.  Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation.

Authors:  Erin E Matthews; Damien Thévenin; Julia M Rogers; Lisa Gotow; Paul D Lira; Lawrence A Reiter; William H Brissette; Donald M Engelman
Journal:  FASEB J       Date:  2011-03-14       Impact factor: 5.191

7.  Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation.

Authors:  Jean-Philippe Defour; Miki Itaya; Vitalina Gryshkova; Ian C Brett; Christian Pecquet; Takeshi Sato; Steven O Smith; Stefan N Constantinescu
Journal:  Proc Natl Acad Sci U S A       Date:  2013-01-28       Impact factor: 11.205

8.  Growth hormone specifically regulates serine protease inhibitor gene transcription via gamma-activated sequence-like DNA elements.

Authors:  D Sliva; T J Wood; C Schindler; P E Lobie; G Norstedt
Journal:  J Biol Chem       Date:  1994-10-21       Impact factor: 5.157

9.  Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients.

Authors:  Xénia Cabagnols; Fabrizia Favale; Florence Pasquier; Kahia Messaoudi; Jean Philippe Defour; Jean Christophe Ianotto; Christophe Marzac; Jean Pierre Le Couédic; Nathalie Droin; Ilyas Chachoua; Remi Favier; M'boyba Khadija Diop; Valérie Ugo; Nicole Casadevall; Najet Debili; Hana Raslova; Christine Bellanné-Chantelot; Stefan N Constantinescu; Olivier Bluteau; Isabelle Plo; William Vainchenker
Journal:  Blood       Date:  2015-10-08       Impact factor: 22.113
  9 in total
  3 in total

1.  Two activating mutations of MPL in triple-negative myeloproliferative neoplasms.

Authors:  Juan Xie; Xiuhua Chen; Feng Gao; Ruixia Hou; Tingting Tian; Yaofang Zhang; Lifang Fan; Jinjun Hu; Guiyang Zhu; Wanfang Yang; Hongwei Wang
Journal:  Cancer Med       Date:  2019-07-11       Impact factor: 4.452

2.  Transforming growth factor β-mediated micromechanics modulates disease progression in primary myelofibrosis.

Authors:  Patric Teodorescu; Sergiu Pasca; Ancuta Jurj; Grigore Gafencu; Jon-Petur Joelsson; Sonia Selicean; Cristian Moldovan; Raluca Munteanu; Anca Onaciu; Adrian-Bogdan Tigu; Mihail Buse; Alina-Andreea Zimta; Rares Stiufiuc; Bobe Petrushev; Minodora Desmirean; Delia Dima; Cristina Vlad; Jon Thor Bergthorsson; Cristian Berce; Stefan Ciurea; Gabriel Ghiaur; Ciprian Tomuleasa
Journal:  J Cell Mol Med       Date:  2020-09-05       Impact factor: 5.310

Review 3.  Functional Consequences of Mutations in Myeloproliferative Neoplasms.

Authors:  Stefan N Constantinescu; William Vainchenker; Gabriel Levy; Nicolas Papadopoulos
Journal:  Hemasphere       Date:  2021-06-01
  3 in total

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