Literature DB >> 28529130

The Future of Drug Development for Neglected Tropical Diseases: How the European Commission Can Continue to Make a Difference.

Raymond J Pierce1, Jane MacDougall2, Rob Leurs3, Maria Paola Costi4.   

Abstract

In this article, the four coordinators of neglected tropical disease (NTD) drug development projects funded under the European Commission (EC) Framework Programme 7 argue that the EC should reassess their funding strategy to cover the steps necessary to translate a lead compound into a drug candidate for testing in clinical trials, and suggest ways in which this might be achieved.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28529130     DOI: 10.1016/j.pt.2017.04.007

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  2 in total

1.  Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei.

Authors:  Michela Cerone; Elisa Uliassi; Federica Prati; Godwin U Ebiloma; Leandro Lemgruber; Christian Bergamini; David G Watson; Thais de A M Ferreira; Gabriella Simões Heyn Roth Cardoso; Luiz A Soares Romeiro; Harry P de Koning; Maria Laura Bolognesi
Journal:  ChemMedChem       Date:  2019-02-05       Impact factor: 3.466

2.  Synthesis and Structure-Activity Relationships of Imidazopyridine/Pyrimidine- and Furopyridine-Based Anti-infective Agents against Trypanosomiases.

Authors:  Daniel G Silva; Anna Junker; Shaiani M G de Melo; Fernando Fumagalli; J Robert Gillespie; Nora Molasky; Frederick S Buckner; An Matheeussen; Guy Caljon; Louis Maes; Flavio S Emery
Journal:  ChemMedChem       Date:  2020-11-11       Impact factor: 3.466

  2 in total

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