| Literature DB >> 28527522 |
Oscar E Streeter1, Phillip J Beron2, Prashant Natarajan Iyer3.
Abstract
Precision medicine is the application of genotypic and Omics biomarkers to determine the most appropriate, outcome-driven therapy for individual patients. To determine the best choice of therapy, institutions use significant information technology-enabled data from imaging, electronic medical records, sensors in the clinic/hospitals, and wearable sensors to determine treatment response. With genomic profiling, targets to affect a disease course are continuing to be developed. As clonal mutational prevalence continues to be understood, information can be communicated to patients to inform them that resistance is common, requiring collection of more genetic mutations from patients with further biopsies or blood collection.Entities:
Keywords: Big data; Checkpoint inhibitors; Genomic profiling; Hyperthermia; Immunotherapy; Machine learning; Precision medicine; Radiogenomics
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Year: 2017 PMID: 28527522 DOI: 10.1016/j.otc.2017.03.012
Source DB: PubMed Journal: Otolaryngol Clin North Am ISSN: 0030-6665 Impact factor: 3.346