| Literature DB >> 28526740 |
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Abstract
The FDA has approved the small-molecule inhibitor midostaurin in combination with chemotherapy to treat acute myeloid leukemia. It is the first approved drug for the disease that specifically targets FLT3 mutations, which occur in about a quarter of all AML cases and are associated with particularly poor outcomes. ©2017 American Association for Cancer Research.Entities:
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Year: 2017 PMID: 28526740 DOI: 10.1158/2159-8290.CD-NB2017-072
Source DB: PubMed Journal: Cancer Discov ISSN: 2159-8274 Impact factor: 39.397