Literature DB >> 2852626

Peroxidation of phospholipids promoted by myeloperoxidase.

G Carlin1, R Djursäter.   

Abstract

Myeloperoxidase was found to promote peroxidation of phospholipids under acidic conditions in the presence of hydrogen peroxide and iodide ions. The peroxidation was markedly enhanced by pyrophosphate-chelated ferric iron and was inhibited by desferrioxamine and superoxide dismutase. This observation adds lipid peroxidation to the oxidative damage caused by myeloperoxidase, which is a phagocytic cell enzyme involved in phagocyte-mediated cell destruction.

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Year:  1988        PMID： 2852626     DOI： 10.3109/10715768809055150

Source DB:  PubMed          Journal:  Free Radic Res Commun        ISSN： 8755-0199


  5 in total

1.  Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal.

Authors:  Dhanalakshmi S Anbukumar; Laurie P Shornick; Carolyn J Albert; Melissa M Steward; Raphael A Zoeller; William L Neumann; David A Ford
Journal:  J Lipid Res       Date:  2009-12-17       Impact factor: 5.922

2.  Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages.

Authors:  L J Hazell; R Stocker
Journal:  Biochem J       Date:  1993-02-15       Impact factor: 3.857

3.  Antioxidant defenses and lipid peroxidation in human blood plasma.

Authors:  B Frei; R Stocker; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

4.  Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation.

Authors:  L J Hazell; J J van den Berg; R Stocker
Journal:  Biochem J       Date:  1994-08-15       Impact factor: 3.857

Review 5.  Strategies to Improve Vaccine Efficacy against Tuberculosis by Targeting Innate Immunity.

Authors:  Ulrich E Schaible; Lara Linnemann; Natalja Redinger; Emmanuel C Patin; Tobias Dallenga
Journal:  Front Immunol       Date:  2017-12-11       Impact factor: 7.561
  5 in total

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