Literature DB >> 28523536

Microenvironment of liver regeneration in liver cancer.

Han-Min Li1,2, Zhi-Hua Ye3,4.   

Abstract

The occurrence and development of liver cancer are essentially the most serious outcomes of uncontrolled liver regeneration. The progression of liver cancer is inevitably related to the abnormal microenvironment of liver regeneration. The deterioration observed in the microenvironment of liver regeneration is a necessary condition for the occurrence, development and metastasis of cancer. Therefore, the use of a technique to prevent and treat liver cancer via changes in the microenvironment of liver regeneration is a novel strategy. This strategy would be an effective way to delay, prevent or even reverse cancer occurrence, development and metastasis through an improvement in the liver regeneration microenvironment along with the integrated regulation of multiple components, targets, levels, channels and time sequences. In addition, the treatment of "tonifying Shen (Kidney) to regulate liver regeneration and repair by affecting stem cells and their microenvironment" can regulate "the dynamic imbalance between the normal liver regeneration and the abnormal liver regeneration"; this would improve the microenvironment of liver regeneration, which is also a mechanism by which liver cancer may be prevented or treated.

Entities:  

Keywords:  liver cancer; liver regeneration microenvironment; tonifying Shen (Kidney) to regulate liver regeneration and repair by affecting stem cells and their microenvironment

Mesh:

Year:  2017        PMID: 28523536     DOI: 10.1007/s11655-017-2806-0

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  31 in total

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Authors:  Guanhua Xie; Anna Mae Diehl
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6.  Serum and tissue vascular endothelial growth factor predicts prognosis in hepatocellular carcinoma patients after partial liver resection.

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7.  Papillary carcinoma of the thyroid: evidence for a role for hepatocyte growth factor (HGF) in promoting tumour angiogenesis.

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8.  Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair.

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9.  HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.

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Review 10.  TGF-β in progression of liver disease.

Authors:  Steven Dooley; Peter ten Dijke
Journal:  Cell Tissue Res       Date:  2011-10-19       Impact factor: 5.249

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  9 in total

1.  A Study on Curcumol Influencing Proliferation and Apoptosis of Hepatocellular Carcinoma Cells through DJ-1/PTEN/PI3K/AKT Pathway.

Authors:  Rongzhen Zhang; Lu Zhong; Kewei Sun; Jiao Liu; Qianna Wang; Dewen Mao; Gang Fang; Fuli Long
Journal:  Biomed Res Int       Date:  2022-05-20       Impact factor: 3.246

2.  RAB9A Plays an Oncogenic Role in Human Liver Cancer Cells.

Authors:  Pengfei Sun; Lei Li; Zhongchao Li
Journal:  Biomed Res Int       Date:  2020-04-30       Impact factor: 3.411

3.  Antitumor activities of novel glycyrrhetinic acid-modified curcumin-loaded cationic liposomes in vitro and in H22 tumor-bearing mice.

Authors:  Mingxiang Chang; Meimei Wu; Hanmin Li
Journal:  Drug Deliv       Date:  2018-11       Impact factor: 6.419

4.  Secreted Protein Acidic and Rich in Cysteine as A Regeneration Factor: Beyond the Tissue Repair.

Authors:  Abdelaziz Ghanemi; Mayumi Yoshioka; Jonny St-Amand
Journal:  Life (Basel)       Date:  2021-01-08

5.  Head and neck cancer exosomes drive microRNA-mediated reprogramming of local neurons.

Authors:  Patrick J Hunt; Moran Amit
Journal:  Extracell Vesicles Circ Nucl Acids       Date:  2020-12-30

6.  Inhibition of miR-15a-5p Promotes the Chemoresistance to Pirarubicin in Hepatocellular Carcinoma via Targeting eIF4E.

Authors:  Ying Zhang; Qingsong Tie; Zhiwei Bao; Zhi Shao; Lan Zhang
Journal:  Comput Math Methods Med       Date:  2021-11-13       Impact factor: 2.238

7.  Midazolam Suppresses Hepatocellular Carcinoma Cell Metastasis and Enhances Apoptosis by Elevating miR-217.

Authors:  Qian Shen; Yanqiong Xia; Leilei Yang; Bo Wang; Jian Peng
Journal:  Comput Math Methods Med       Date:  2022-03-09       Impact factor: 2.238

8.  A comprehensive investigation on liver regeneration: a meta-analysis and systems biology approach.

Authors:  Solmaz Asnaashari; Elham Amjad; Babak Sokouti
Journal:  Clin Exp Hepatol       Date:  2021-06-30

9.  3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy.

Authors:  Fangfang Zhao; Guohe Feng; Junyao Zhu; Zhijun Su; Ruyi Guo; Jiangfu Liu; Huatang Zhang; Yongzhen Zhai
Journal:  Anticancer Drugs       Date:  2021-04-01       Impact factor: 2.389

  9 in total

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